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UnknownLiquid biopsy perspectives in pleomorphic carcinoma of the lung: case report.

Background

Liquid biopsy has recently made it possible to use minimally invasive testing to examine tumor-derived material released into peripheral blood, including circulating tumor cells (CTCs), extracellular vesicles (EVs), and circulating tumor deoxyribonucleic acid (ctDNA). Lung pleomor...
S-EPMC12261257 | biostudies-literature
UnknownUnravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease.
The plasmacytoma variant translocation 1 (PVT1) is a long non-coding RNA gene involved in human disease, mainly in cancer onset/progression. Although widely analysed, its biological roles need to be further clarified. Notably, functional studies on PVT1 are complicated by the occurrence of multiple ...
S-EPMC8927338 | biostudies-literature
UnknownAssociation between Type-D Personality and Affective (Anxiety, Depression, Post-traumatic Stress) Symptoms and Maladaptive Coping in Breast Cancer Patients: A Longitudinal Study.

Background

Type-D (distressed) personality has not been prospectively explored for its association with psychosocial distress symptoms in breast cancer patients.

Objective

The objective of the study was to test the hypothesis that Type-D personality can be associated with psychosocial...
S-EPMC8985468 | biostudies-literature
UnknownD-lactate and glycerol as potential biomarkers of sorafenib activity in hepatocellular carcinoma.
Sorafenib, a multi-kinase inhibitor for advanced hepatocellular carcinoma (HCC), often encounters resistance within months of treatment, limiting its long-term efficacy. Despite extensive efforts, reliable plasma biomarkers to monitor drug activity remain elusive. Here, we demonstrate that metabolic...
S-EPMC12202795 | biostudies-literature
UnknownPatient centered radiology: investigating 3 Tesla whole body MRI acceptance in cancer patients.

Introduction

Whole body magnetic resonance imaging (WB-MRI) is a promising emerging imaging technology for detecting bone and soft tissue pathology, especially in the onco-hematological field. This study aims to evaluate cancer patients' experience of WB-MRI performed on a 3T scanner compare...
S-EPMC10338551 | biostudies-literature
UnknownFirst step results from a phase II study of a dendritic cell vaccine in glioblastoma patients (CombiG-vax).

Background

Glioblastoma (GBM) is a poor prognosis grade 4 glioma. After surgical resection, the standard therapy consists of concurrent radiotherapy (RT) and temozolomide (TMZ) followed by TMZ alone. Our previous data on melanoma patients showed that Dendritic Cell vaccination (DCvax) could ...
S-EPMC11347333 | biostudies-literature
UnknownFrom phenotypical investigation to RNA-sequencing for gene expression analysis: A workflow for single and pooled rare cells.
Combining phenotypical and molecular characterization of rare cells is challenging due to their scarcity and difficult handling. In oncology, circulating tumor cells (CTCs) are considered among the most important rare cell populations. Their phenotypic and molecular characterization is necessary to ...
S-EPMC9703136 | biostudies-literature
UnknownAssociation between Pre-Treatment Biological Indicators and Compliance to Neoadjuvant/Perioperative Chemotherapy in Operable Gastric Cancer.

Background and aims

Perioperative treatment is currently the gold standard approach in Europe for locally advanced gastric cancer (GC). Unfortunately, the phenomenon of patients dropping out of treatment has been frequently observed. The primary aims of this study were to verify if routine b...
S-EPMC10458231 | biostudies-literature
UnknownRadiomics Analysis on [68Ga]Ga-PSMA-11 PET and MRI-ADC for the Prediction of Prostate Cancer ISUP Grades: Preliminary Results of the BIOPSTAGE Trial.
Prostate cancer (PCa) risk categorization based on clinical/PSA testing results in a substantial number of men being overdiagnosed with indolent, early-stage PCa. Clinically non-significant PCa is characterized as the presence of ISUP grade one, where PCa is found in no more than two prostate biopsy...
S-EPMC9028386 | biostudies-literature
UnknownRole of Hyperbaric Oxygenation Plus Hypofractionated Stereotactic Radiotherapy in Recurrent High-Grade Glioma.

Background

The presence of hypoxic cells in high-grade glioma (HGG) is one of major reasons for failure of local tumour control with radiotherapy (RT). The use of hyperbaric oxygen therapy (HBO) could help to overcome the problem of oxygen deficiency in poorly oxygenated regions of the tumou...
S-EPMC8042328 | biostudies-literature
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