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TranscriptomicsOrientia tsutsugamushi, the agent of scrub typhus, induces an inflammatory program in human macrophages
Scrub typhus is a life-threatening disease caused by Orientia tsutsugamushi, a bacterium that mainly infects endothelial cells in vitro and in vivo. Evidence suggests that the interaction of O. tsutsugamushi with myeloid cells may play a pivotal role in O. tsutsugamushi infection. We showed here tha...
ORGANISM(S): Homo sapiens 
2013-01-29 | E-GEOD-38194 | biostudies-arrayexpress
TranscriptomicsThe multifaceted responses of human monocytes to IFN-gamma and IL-4 are not reducible to M1/M2 polarization of Macrophages
Macrophages are known to be polarized into inflammatory (M1) and immunoregulatory (M2) cells when they are stimulated by agonists such as IFN-gamma and IL-4, respectively. If circulating monocytes may be polarized in response to T cell signals is often misguidedly deduced from macrophage results. He...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-GEOD-36537 | biostudies-arrayexpress
TranscriptomicsEvaluation of the effects of Lactobacillus sp. (ostrich) on body weight, the intestinal microbiome and metabolism in mice
Background. Food can affect the microbial balance in the human intestine, and the ingestion of probiotics may play a role in the current obesity pandemic. The objective of our study was to determine if increased Lactobacillus spp. in the intestinal microflora of mice can promote growth and if change...
ORGANISM(S): Mus musculus 
2010-09-21 | E-GEOD-24219 | biostudies-arrayexpress
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