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TranscriptomicsThe small RNA repertoire of Dictyostelium discoideum
Small RNAs play crucial roles in regulation of gene expression in many eukaryotes. Here, we report the cloning and characterization of 18-26 nt RNAs in the social amoeba Dictyostelium discoideum. This survey uncovered developmentally regulated microRNA candidates whose biogenesis, at least in one ca...
ORGANISM(S): Dictyostelium discoideum 
2007-10-16 | E-GEOD-8755 | biostudies-arrayexpress
TranscriptomicsStaufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans
The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly sup...
ORGANISM(S): Caenorhabditis elegans 
2016-03-16 | E-GEOD-79217 | biostudies-arrayexpress
TranscriptomicsAIN-2::GFP IP of mRNAs associated with miRISC in stage sychronized C. elegans populations
AIN-2::GFP IP were used to purify miRISC from stage sychronized C.elegans populations (Egg, L1, L2, L3 and L4 stages). The mRNA composition of the IP results and the corresponding total RNA samples were analyzed by WUSTL Caenorhabditis elegans Whole Genome 23k Oligo Array. The miRISC associated mRNA...
ORGANISM(S): Caenorhabditis elegans 
2009-05-21 | E-GEOD-16208 | biostudies-arrayexpress
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