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GenomicsRNA-seq of AMFR mutant human in vitro differentiated neural stem cells
RNA-seq of AMFR mutant human in vitro differentiated neural stem cells
PRJNA834782 | ENA
TranscriptomicsRNA-seq of AMFR mutant human in vitro differentiated neural stem cells
We report transcriptome analysis of human in vitro differentiated neural stem cells (derived from H9 human embryonic stem cells), comparing wild type and AMFR homozygous knock-out mutant cells. To model a novel genetic disorder caused by bi-allelic loss-of-function variants in AMFR and to study the ...
ORGANISM(S): Homo sapiens 
2023-04-29 | GSE202141 | GEO
UnknownAMFR-mediated Flavivirus NS2A ubiquitination subverts ER-phagy to augment viral pathogenicity.
Not available
S-EPMC11541587 | biostudies-literature
UnknownER-phagy Activation by AMFR Attenuates Cardiac Fibrosis Post-Myocardial Infarction via mTORC1 Pathway.
Not available
S-EPMC12499418 | biostudies-literature
ProteomicsE3 ligase AMFR regulates ARL6IP1 Ubiquitination in cells
ER-resident membrane-shaping proteins with central reticulon homology domains (RHDs) have been associated with neurodegenerative disorders such as ARL6IP1 and FAM134B.Mutations in ARL6IP1 cause SPG61, a neurodegenerative disorder characterized by progressive leg spasticity (hereditary spastic parapl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD039184 | Pride
Amfr Arl6ip1 ubiquitination 
UnknownAMFR drives allergic asthma development by promoting alveolar macrophage-derived GM-CSF production.
Not available
S-EPMC8961293 | biostudies-literature
UnknownPharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
Not available
S-EPMC9462477 | biostudies-literature
UnknownAMFR-mediated ER-phagy regulation and therapeutic targeting in osteosarcoma: a multifunctional nanoplatform strategy.
Not available
S-EPMC12625341 | biostudies-literature
UnknownCharacterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus.
Not available
S-EPMC107543 | biostudies-literature
UnknownAMFR and DCTN2 genes cause transplantation resistance of adipose-derived mesenchymal stem cells in type 1 diabetes mellitus
Not available
S-EPMC9577117 | biostudies-literature
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