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Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major outstanding question is the degree to which the biofilm-specific cellular state and its constituent genetic determinants contribute to this hyper-tolerant phenotype. Here, using genome-wide functional...
ORGANISM(S): Pseudomonas aeruginosa 
The goal of this experiment is to identify the pathways that are deregulated as part of an adaptive response to high levels of ethanol in the media. Ethanol tolerant cells (HG228) grown in minimal media plus 1.5% (v/v) ethanol were hybridized against E. coli MG1655 grown under similar conditions. Th...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
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