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ProteomicsDistinct branches of the N-end rule pathway modulate the plant immune response
The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, though little information exists regarding biological roles. Here we show that the cysteine (Cys-) and glutamine (Gln)-specific amino-terminal (Nt)-amidase NTAQ1 branches are both components of the plant imm...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-11-06 | PXD008520 | Pride
Ntaq N-end rule pathway Plant immunity Erfvii Amino-terminal glutamine amidase 
TranscriptomicsSmall RNAs in H9 embryonic stem cells
Non-templated 3'-end oligouridylation of RNA occurs in many species, including humans. Unlike the familiar phenomenon of polyadenylation, non-templated addition of uridines to RNA is poorly characterized in higher eukaryotes. Recent studies have reported non-templated 3'-end oligouridylation of smal...
ORGANISM(S): Homo sapiens 
2012-03-21 | E-GEOD-31051 | biostudies-arrayexpress
TranscriptomicsGenome-Wide STAT5 binding sites in Kit225 leukemia cells
In order to systematically map STAT5 genomic binding sites and IL-2 mediated gene expression changes we mapped STAT5 binding sites using chip-on-ChIP in IL-2 dependent Kit225 cells that were either left un-stimulated or stimulated with IL-2 for 30 minutes. Using MAT analysis we identified 1581 STAT5...
ORGANISM(S): Homo sapiens 
2013-03-21 | E-GEOD-40619 | biostudies-arrayexpress
TranscriptomicstRNA fragment profiling in CLP1 mutant (kinase-dead) mice
Loss of CLP1 activity results in the accumulation of novel sets of small RNA fragments derived from aberrant processing of tyrosine pre-tRNA. Such tRNA fragments sensitize cells to oxidative stress-induced p53 activation and p53-dependent cell death. 2 samples, Wt and Clp1(k/k), no replicates
ORGANISM(S): Mus musculus 
2013-04-03 | E-GEOD-39275 | biostudies-arrayexpress
TranscriptomicsGenome-wide mapping of IL-2 regulated target genes and IL-2 activated STAT5 binding sites in Kit225 human leukemia cells.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-03-21 | E-GEOD-40624 | biostudies-arrayexpress
TranscriptomicsIL-2 induced gene expression changes in Kit225 human leukemia cell lines
Identify IL-2 mediated genes in Kit225 cells. IL-2 withdrawn cells were treated with IL-2 or left untreated for 3 hours and then subjected to gene expression microarray analysis.
ORGANISM(S): Homo sapiens 
2013-03-21 | E-GEOD-40618 | biostudies-arrayexpress
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