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The v-erbA oncogene belongs to a superfamily of transcription factors called nuclear receptors, which includes the retinoic acid receptors (RARs) responsible for mediating the effects of retinoic acid (RA). Nuclear receptors bind to specific DNA sequences in the promoter region of target genes and v...
ORGANISM(S): Mus musculus 
RNA sequencing of murine hepatocyte cell line AML12 treated with palmitic acid
Transcriptional profiling of murine hepatocyte gene expression following exposure to prolactin or actinomycin D Prolactin or actinomycin D-treated versus serum-free control cells: AML12 and Hepa 1-6. Biological replicates: 2 per cell line per treatment protocol.
ORGANISM(S): Mus musculus 
We identified the ubiquitin ligase Uhrf2 as an important regulator of liver regeneration. To gain insight into the mechanisms of action of Uhrf2 in hepatocytes, we searched for Uhrf2 interactors in the AML12 hepatocyte cell line using BioID interaction screening. This resulted in the identification ...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-01 | PXD041732 | Pride
We investigated genome-wide DNA methylation during EMT in AML12 cells using comprehensive high throughput arrays for relative methylation (CHARM). We used custom Nimblegen microarrays. We isolated genomic DNA from cells at different timepoints post-TGF-β stimulation and hybridized to custom-designed...
ORGANISM(S): Mus musculus 
Gene expression analysis of wildtype AML12 versus VWA8-null AML12 cells
Irisin regulated genes in mouse liver derived AML12 cells
Expression (Gene) array from AMl12-Zfp125- stably expressing cells
In vitro modeling of hepatic aging using AML12 cells
Gene expression in AML12 cells after Uhrf2 knock-down
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