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TranscriptomicsGlobal gene profiling of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-induced neuronal death
AMPA receptors are involved not only in neuronal plasticity but also in excitotoxicity, mediated largely by the influx of Ca2+ (Choi et al., 1988). Their implication has been highlighted in animal models of ischemia and epilepsy. Studies of ischemic rodent models featured that prior to cell death, h...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-22993 | biostudies-arrayexpress
ModelsDutta-Roy2015 - Opening of the multiple AMPA receptor conductance states
Dutta-Roy2015 - Opening of the multiple AMPA receptor conductance states This model is described in the article: Ligand-dependent opening of the multiple AMPA receptor conductance States: a concerted model. Dutta-Roy R, Rosenmund C, Edelstein SJ, Le Novère N. PLoS ONE 2015...
2024-09-02 | BIOMD0000000569 | BioModels
ProteomicsA Noelin-organized extracellular network of proteins required for constitutive and context-dependent anchoring of AMPA-receptors
Information processing and storage in the brain rely on AMPA-receptors (AMPARs) and their context-dependent dynamics in synapses and extra-synaptic sites. We found that distribution and dynamics of AMPARs in the plasma membrane are controlled by Noelins, a three-member family of conserved secreted p...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2024-03-13 | PXD041655 | Pride
Ampa receptors Proteomics Molecular neuroscience 
ProteomicsSorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2
The endosome-associated cargo adaptor sorting nexin-27 (SNX27) is linked to various neuropathologies through sorting of integral proteins to the synaptic surface, most notably AMPA receptors. To provide a broader view of SNX27-associated pathologies we performed proteomics in rat primary neurons to ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-06-28 | PXD026289 | Pride
Membrane trafficking Snx27 Lrfn2 Ampa receptors 
GenomicsBAI1 localises AMPA receptors at the cochlear afferent postsynaptic density and is
BAI1 localises AMPA receptors at the cochlear afferent postsynaptic density and is
PRJNA1069109 | ENA
ProteomicsDynamic extracellular interactions with AMPA receptors
Extracellular AMPA receptors regulation with broad implications for synapse function and synaptic plasticity
ORGANISM(S): Rattus Sp. (ncbitaxon:10118) 
2025-10-23 | MSV000099578 | MassIVE
GenomicsBlockage of Ca2+-permeable AMPA receptors suppresses proliferation of schwannoma cells
Blockage of Ca2+-permeable AMPA receptors suppresses proliferation of schwannoma cells
PRJNA1479987 | ENA
TranscriptomicsBAI1 localises AMPA receptors at the cochlear afferent postsynaptic density and is
Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming axo-somatic synapses with inner hair cells (IHCs), the primary sensory receptors of the mammalian cochlea. Although IHC ribbon synapses have been extensively studied, the molecular mechanisms re...
ORGANISM(S): Mus musculus 
2024-03-27 | GSE254269 | GEO
ProteomicsTemporal quantitative proteomics of mGluR-induced protein translation and phosphorylation in neurons
At neuronal synapses, activation of group I metabotropic glutamate receptors (mGluR1/5) triggers a form of long-term depression (mGluR-LTD) that relies on new protein synthesis and the internalization of AMPA-type glutamate receptors. Dysregulation of these processes has been implicated in the devel...
ORGANISM(S): Rattus Norvegicus 
2020-10-27 | PXD020777 | panorama
GenomicsEarly Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors
Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors
PRJNA1462345 | ENA
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