Sort   by:  
 Page size 
TranscriptomicsA genome-wide genetic interaction screen reveals metabolic roles of human histone deacetylase 1
Dynamic acetylation of metabolic proteins has emerged as a ubiquitous post-translational modification of human metabolic proteins. However, the corresponding modifying enzymes and the functions of the modification await exploration. Using a genome-wide synthetic lethality screen, we constructed a ge...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-29662 | biostudies-arrayexpress
ProteomicsAP-MS of C18ORF25 with AMPK- and S67 phosphorylation-depedent interactions
C18ORF25 is a homolog of Arkadia (RNF111), an E3 ubiquitin ligase with SUMO-interaction motifs (SIMs) (PMID: 31417085). However, C18ORF25 lacks the entire C-terminal RING domain of RNF111 which is required for ubiquitin binding suggesting it lacks ubiquitination activity and may therefore act as an ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-03 | PXD045629 | Pride
C18orf25 Ampk phosphorylation dependent protein interactions Exercise 
UnknownAMPK-dependent phosphorylation of cingulin reversibly regulates its binding to actin filaments and microtubules.
Not available
S-EPMC6195624 | biostudies-literature
TranscriptomicsPKA-dependent Phosphorylation of A Histone Demethylase Drives Higher Order Chromatin Structures by Association with SWI/SNF Chromatin Remodeler
The current studies show that JMJD1A is phosphorylated at S265 by protein kinase A (PKA), and this is pivotal to activate expression of the b1-adrenergic receptor gene (Adrb1) and downstream targets including Ucp1. Phosphorylation of JMJD1A increases its interaction with the SWI/SNF nucleosome remod...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-58936 | biostudies-arrayexpress
ModelsHIV-1 interactions with T Cell Signalling Pathway
Motivation: Human immunodeficiency virus type 1 (HIV-1) hijacks host cellular processes to replicate within its host. Through interactions with host proteins, it perturbs and interrupts signaling pathways that alter key cellular functions. Although networks of viralhost interactions have been relati...
2738 | Cell Collective
UnknownStructural models of CFTR-AMPK and CFTR-PKA interactions: R-domain flexibility is a key factor in CFTR regulation.
Not available
S-EPMC3249538 | biostudies-literature
TranscriptomicsHNF4α is a therapeutic target that links AMPK to WNT signaling in early-stage gastric cancer
Background Worldwide, gastric cancer is the fourth most common malignancy and the most common cancer in East Asia. Development of targeted therapies for this disease has focused on a few known oncogenes but has had limited effects. Objective To determine oncogenic mechanisms and novel therapeutic ta...
ORGANISM(S): Homo sapiens 
2014-11-15 | E-GEOD-63288 | biostudies-arrayexpress
UnknownParticipation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase.
Not available
S-EPMC4380640 | biostudies-literature
UnknownAutophagy Dually Induced by AMP Surplus and Oxidative Stress Enhances Hemocyte Survival and Bactericidal Capacity via AMPK Pathway in Crassostrea hongkongensis.
Not available
S-EPMC7325953 | biostudies-literature
UnknownAnti-Obesity and Lipid Lowering Activity of Bauhiniastatin-1 is Mediated Through PPAR-γ/AMPK Expressions in Diet-Induced Obese Rat Model.
Not available
S-EPMC8341109 | biostudies-literature
Sort   by:  
 Page size