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ProteomicsAnalysis of neutrophil proteome of Barth syndrome patients
Barth syndrome (BTHS) is a rare genetic disease caused by mutations in the TAFAZZIN gene. It is characterized by neutropenia, cardiomyopathy, and skeletal myopathy. Neutropenia in BTHS is associated with life-threatening infections, yet the molecular and physiological causes of this phenomenon are p...
ORGANISM(S): Homo sapiens (Human) 
2025-02-12 | PXD052714 | Pride
Neutrophil Barth 
ProteomicsNeutrophil proteomic changes associated with sepsis
To identify potential targetable mechanisms controlling neutrophil degranulation in systemic infection, we investigated alterations in neutrophil developmental state under severe inflammation. We performed tandem mass tag (TMT) proteomics on neutrophils isolated from peripheral blood of sepsis patie...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD076155 | Pride
Sepsis Neutrophil 
ProteomicsNeutrophil proteome of severe malaria adult patients in Mozambique
Malaria is a truly devastating global disease, with over 240 million infections and over 600,000 deaths reported annually worldwide, with deaths occurring mainly in children under 5 years old. Malaria is caused by infection with the Plasmodium parasite, which infects erythrocytes and promotes seques...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD052711 | Pride
Malaria Neutrophil 
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