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ProteomicsHuman Calcitonin and Amylin receptor HDX-MS
Receptor activity-modifying proteins (RAMPs) regulate the pharmacology, trafficking, and signaling of class B1 G protein-coupled receptors (GPCRs). The calcitonin receptor (CTR) interacts with each of the three RAMPs to form amylin receptors (AMYRs), which display distinct ligand preferences and sig...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD068848 | Pride
Calcitonin recepto Hdx-ms Recepror activity modifying protein (ramp) Gpcr Amylin receptor 
TranscriptomicsTranscription profiling of mouse pancreatic beta cell line (MIN6) treated with amylin at different times and doses and growth at different concentrations of glucose
Murine pancreatic beta cell line MIN6 was growth at two different concentrations of glucose (22,2 and 5,5 mM of glucose), 37ºC, 5% CO2 and was treated at four different concentrations of human amylin (0, 1, 10 and 20 uM) during three different times (2, 12 and 24 hours)
ORGANISM(S): Mus musculus 
2009-04-10 | E-GEOD-2253 | biostudies-arrayexpress
TranscriptomicsGene expression induced by LPS, two amyloidogenic peptides, Tau 623-628 and Amylin 28-33, in peritoneal macrophages and B1a cells
Amyloidogenic peptides are therapeutic in EAE, reducing systemic levels of IL6, TNF, and INFg. The fibrils are bound and endocytosed in peritoneal MFs and B1a cells. Differential gene expression was used to further understand the process. Groups of three female C57BL/6 mice were injected with 10ug o...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-73026 | biostudies-arrayexpress
UnknownAmylin receptor ligands reduce the pathological cascade of Alzheimer's disease.
Not available
S-EPMC6511375 | biostudies-literature
GenomicsCagrilintide lowers bodyweight through brain amylin receptors 1 and 3
Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3
PRJNA1259490 | ENA
UnknownMolecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin.
Not available
S-EPMC7088893 | biostudies-literature
UnknownAmyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants.
Not available
S-EPMC7656518 | biostudies-literature
UnknownDeconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor.
Not available
S-EPMC7088965 | biostudies-literature
UnknownAmylin receptor components and the leptin receptor are co-expressed in single rat area postrema neurons.
Not available
S-EPMC10704335 | biostudies-literature
UnknownShort amylin receptor antagonist peptides improve memory deficits in Alzheimer's disease mouse model.
Not available
S-EPMC6662706 | biostudies-literature
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