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MetabolomicsPlatycodin D attenuates alcohol-associated fatty liver disease by suppressing TLR4–NF-κB and activating PPAR signaling

Alcohol-associated fatty liver disease (AFLD) is driven by ethanol-induced metabolic dysregulation and hepatic inflammation, with gut dysbiosis and endotoxin-triggered innate immune activation implicated in disease progression. Platycodin D (PD), a triterpenoid saponin from Platycodon grandifloru...

2026-01-12 | MTBLS13658 | MetaboLights
MetabolomicsPTER is an N-acetyltaurine hydrolase that regulates feeding and obesity

Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans1-3. In endogenous taurine metabolism, dedicated enzymes are involved in biosynthesis of taurine from cysteine as well as the downstream metabolism of secondary taurine metabolites4,5. One such ta...

2024-09-11 | MTBLS10408 | MetaboLights
TranscriptomicsComparison of testes gene expression of D. melanogaster species and their hybrids
Males hybrids from the crosses between species of the D. simulans clade are steriles as the females are fertiles. Hybrid male sterility is due to severe defects in spermatogenesis and phenotypic differences are observed between the different hybrids involving D. simulans, D. sechellia and D. mauriti...
ORGANISM(S): Drosophila melanogaster 
2006-06-11 | E-GEOD-3673 | biostudies-arrayexpress
MetabolomicsApolipophorin-III modulates antiviral defense in Bombyx mori: an integrated transcriptomic and lipidomic analysis of its inhibitory role against BmNPV infection.

The silkworm (Bombyx mori) is an economically important insect and a lepidopteran model organism. Controlling viral infections is crucial for the sustainable development of sericulture. Bombyx mori nucleopolyhedrovirus (BmNPV) infection can cause large-scale mortality in silkworm populations. Ins...

2025-12-03 | MTBLS13447 | MetaboLights
TranscriptomicsU87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
U87MG is a commonly studied grade IV glioma cell line that has been analyzed in at least 1,700 publications over four decades. In order to comprehensively characterize the genome of this cell line and to serve as a model of broad cancer genome sequencing, we have generated greater than 30x genomic s...
ORGANISM(S): Homo sapiens 
2010-01-24 | E-GEOD-19986 | biostudies-arrayexpress
UnknownThe VIVID trial 12-month outcomes of the venous stent for the iliofemoral vein using the Duo venous stent system.
Not available
S-EPMC12014339 | biostudies-literature
UnknownPhylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis.
Not available
S-EPMC10394638 | biostudies-literature
UnknownDual guidance structure for evaluation of patients with unclear diagnosis in centers for rare diseases (ZSE-DUO): study protocol for a controlled multi-center cohort study.
Not available
S-EPMC8842899 | biostudies-literature
TranscriptomicsCopy number profiling of PE ovarian cancer lines
The PEO/PEA series of ovarian cancer cell lines was established in 1988 from progressive samples from three separate cases of ovarian cancer (Langdon et al., 1988). Copy number profiling of PE lines on Illumina Infinium Human1M-Duo v3 BeadChips
ORGANISM(S): Homo sapiens 
2010-06-28 | E-GEOD-18461 | biostudies-arrayexpress
TranscriptomicsSorghum nitrogen stress tolerance
Sorghum is an important cereal crop, which requires large quantities of nitrogen fertilizer for achieving commercial yields. Identification of the genes responsible for low-N tolerance in sorghum will facilitate understanding of the molecular mechanisms of low-N tolerance, and also facilitate the ge...
ORGANISM(S): Sorghum bicolor 
2014-05-01 | E-GEOD-54705 | biostudies-arrayexpress
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