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Gold nanoparticle (Au—NP) oligonucleotide complexes hold considerable promise as an approach for manipulating intracellular gene regulation. We show that the uptake and intracellular fate of Au—NP oligonucleotide complexes is associated with endocytosis and signal transduction. A transcriptomeâ€...
ORGANISM(S): Homo sapiens 
Combined gene expression and DNA occupancy profiling identifies JAK/STAT signaling as a valid therapeutic target of t(8;21) AML t(8;21) is commonly associated with acute myeloid leukemia (AML). The resulting AML1-ETO fusion proteins are involved in the pathogenesis of AML. To identify novel molecul...
ORGANISM(S): Mus musculus 
We performed that comprehensive identification of genes responsible for stress tolerance by analyzing the whole-genome expression profiles of poplar (Populus alba M-CM-^W P. glandulosa) leaves exposed to drought and salt stresses. Examination at the molecular level how this tree species responds to ...
ORGANISM(S): Populus alba x Populus glandulosa 
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