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Through RNA sequencing of CD4+ Tmemory/effector cells derived from the synovium of JIA patients and healthy controls, we analyzed the JIA gene expression signature. Treatment of autoinflammatory site-derived patient T cells with the BET-inhibitor JQ1 inhibited immune-related super-enhancers and pref...
ORGANISM(S): Homo sapiens 
Gene expression on peripheral blood mononuclear cells (PBMC) from SPARKS CHARMS juvenile idiopathic arthritis (JIA) cohort pre and post methotrexate therapy. This is the first study to our knowledge, to evaluate gene expression profiles in children with JIA before and after MTX, and to analyze genet...
ORGANISM(S): Homo sapiens 
Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...
ORGANISM(S): Homo sapiens 
We developed a novel approach, J-binding protein 1 sequencing (JBP1-seq), that combines the benefits of an improved recombinant JBP1 protein, Nextera-based library construction, and nextgeneration sequencing (NGS) for genome-wide profiling of 5-hydroxymethylcytosine (5hmC). Compared with the orig...
ORGANISM(S): Homo sapiens 
Purification of RecJ3/4-RNase J complex from Haloferax.volcanii
ORGANISM(S): Haloferax volcanii DS2 
2023-06-22 | PXD019898 | Pride
detecting core complex formation for RecJ3/4 and RNase J form a core complex.
ORGANISM(S): Haloferax volcanii DS2 
2023-06-22 | PXD019932 | Pride
RNAse J, HVO_2724 from halophilic archaeon to identify the proteins it associates with
ORGANISM(S): Haloferax volcanii DS2 
2023-06-22 | PXD019896 | Pride
mRNA trafficking and local protein translation are associated with protrusive cellular domains, such as neuronal growth cones, and deregulated control of protein translation is associated with tumor malignancy. We show here that activated RhoA, but not Rac1, is enriched in pseudopodia of MSV-MDCK-IN...
ORGANISM(S): Canis lupus familiaris 
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