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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
UnknownGlobal disease burden of stroke attributable to high fasting plasma glucose in 204 countries and territories from 1990 to 2019: An analysis of the Global Burden of Disease Study.
Not available
S-EPMC9426282 | biostudies-literature
UnknownActivities of Daily Living of Home Healthcare Patients.
Not available
S-EPMC6506182 | biostudies-literature
MetabolomicsMicroRNA-mediated regulation of lipid metabolism in virus-infected Emiliania huxleyi.
The interactions between Emiliania huxleyi and E. huxleyi virus (EhV) regulate marine carbon and sulfur biogeochemical cycles and play a prominent role in global climate change. As a large DNA virus, EhV has developed a novel 'virocell metabolism' model to meet its high metabolic needs. Although it ...
2024-01-16 | MTBLS5178 | MetaboLights
MetabolomicsEffects of MeJA on Arabidopsis metabolome under endogenous JA deficiency
Jasmonates (JAs) play important roles in plant growth, development and defense. Comprehensive metabolomics profiling of plants under JA treatment provides insights into the interaction and regulation network of plant hormones. Here we applied high resolution mass spectrometry based metabolomics appr...
2017-10-23 | MTBLS375 | MetaboLights
ProteomicsIdentification of human gene LOC107984012 interacting proteins in AC16 cardiomyocytes by pull-down assays coupled to MS
In this study, pull down assays combined with mass spectrometry analysis were performed in AC16 cardiomyocytes transfected with control plasmid (OE-Vector) or LOC107984012-overexpression plasmid to identify the repertoire of LOC107984012 interacting proteins. Pierce™ Magnetic RNA-Protein Pull-Down K...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037001 | Pride
Human gene loc107984012 
ProteomicsIdentification of mouse lncRNA ENSMUST00000219456(GM32255) interacting proteins in HL-1 cardiomyocytes by pull-down assays coupled to MS
In this study, pull down assays combined with mass spectrometry analysis were performed in HL-1 cardiomyocytes transfected with control plasmid (OE-Vector) or LOC107984012-overexpression plasmid to identify the repertoire of LOC107984012 interacting proteins.
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD036966 | Pride
Mouse lncrna ensmust00000219456(gm32255) 
ProteomicsMulti-omics integrative analysis reveals that burdock seed aglycone alleviates renal fibrosis by restoring mitochondrial oxidative phosphorylation function
Renal fibrosis (RF) is a common pathological process in the progression of chronic kidney disease (CKD) to end-stage renal failure and is also a key target for the prevention and treatment of kidney diseases. It is closely associated with mitochondrial dysfunction, particularly impaired oxidative ph...
ORGANISM(S): Rattus Norvegicus 
2026-02-06 | PXD074134 |
UnknownTranslational profile of coding and non-coding RNAs revealed by genome wide profiling of ribosome footprints in grapevine.
Not available
S-EPMC9944039 | biostudies-literature
MetabolomicsThe Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Summary

Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in ciliopathies, since the outer segments (OSs) of photoreceptors are highly specialized primary cilia. BBS...

2022-02-18 | MTBLS4013 | MetaboLights
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