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Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear a...
ORGANISM(S): Mus musculus 
Total RNA was extracted from 3-week-old WT and dja6 dja5 seedlings grown on MS medium. RNA sequencing libraries were constructed and subjected to sequencing using an Illumina Hiseq 2500 platform. After a quality control, the gene expression profiling analysis was performed based on the number of tag...
ORGANISM(S): Arabidopsis thaliana 
The zebrafish embryo has repeatedly proved to be a useful model for the analysis of effects by environmental toxicants. This study was performed to investigate if an approach combining mechanism-specific bioassays with microarray techniques can obtain more in-depth insights into the ecotoxicity of c...
ORGANISM(S): Danio rerio 
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