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MetabolomicsDrought Stress-Induced Physiological and Molecular Changes in Strawberries: An Integrated Transcriptomic and Metabolomic Perspective

This study identifies drought-responsive differential metabolites in two strawberry cultivars ('Benihoppe' and 'Kaorino') via metabolomics, uncovering their genotype-specific metabolic mechanisms of drought tolerance. It provides metabolic-level evidence for breeding drought-resistant strawberrie...

2025-11-22 | MTBLS13366 | MetaboLights
MetabolomicsOPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response

Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular organelles play pivotal roles in the regulation of ferroptosis, but the mechanisms underlying the contributions of the mitochond...

2025-07-14 | MTBLS10544 | MetaboLights
MetabolomicsMass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an in vitro system. Over the past decade, with the advent of spatial technologies,...

2023-05-23 | MTBLS7565 | MetaboLights
MetabolomicsMicrobiome network remodeling drives soil lipid metabolism under safflower cropping systems at different sites: An omics-based dissection
This study investigated the effects of three planting pattern–location combinations (PLMEs) on safflower rhizosphere soil microbiota and metabolic functions: soybean-safflower rotation at Chenghai (CH), tobacco–safflower rotation at Longpan (ZYHY), and apple orchard intercropping at Lijiang(LJ). Eac...
2026-07-22 | MTBLS15129 | MetaboLights
MetabolomicsEcological adaptation and succession of human fecal microbial communities in an automated in vitro fermentation system
Longitudinal studies of gut microbiota following specific interventions are vital for understanding how they influence host health. However, robust longitudinal sampling of gut microbial communities is a major challenge, which can be addressed using in vitro fermenters hosting complex microbial comm...
2021-07-15 | MTBLS2531 | MetaboLights
MetabolomicsUrinary Ubiquitin-Specific Protease 2 (USP2) as a Diagnostic Biomarker for Chronic Kidney Disease: An Integrated Multi-Omics and Network Analysis
Urinary USP2 is elevated in chronic kidney disease and shows strong diagnostic performance. Integrated metabolomics and proteomics analyses identified cortisol and prostaglandin A3 as candidate mediators and linked USP2 to lipid metabolism and ferroptosis-related pathways.
2026-05-05 | MTBLS14426 | MetaboLights
MetabolomicsUntargeted LC–MS metabolomics of Chlorella vulgaris under different carbon-source conditions

This study presents untargeted LC–MS/MS metabolomics and lipidomics datasets comparing CON and MAL experimental groups acquired in both positive and negative electrospray ionization modes. For quality control, a pooled QC sample was prepared by mixing equal volumes of all study samples and was an...

2026-01-20 | MTBLS13731 | MetaboLights
UnknownStructural basis of Q-dependent transcription antitermination.
Not available
S-EPMC6606751 | biostudies-literature
ProteomicsIntegrated DIA proteomics and lipidomics analysis on non-small cell lung cancer patients with TCM syndromes
Lung cancer remains the leading cause of mortality from malignant tumors, non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases, and individualized diagnosis and treatment in traditional Chinese Medicine (TCM) is an effective trend. In this study, a proteomics research wi...
ORGANISM(S): Homo Sapiens 
PXD024704 |
UnknownDescription of Alvaniawangi Xu, Qi & Kong, sp. nov. (Mollusca, Gastropoda, Littorinimorpha, Rissoidae) from the East China Sea.
Not available
S-EPMC10426732 | biostudies-literature
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