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ProteomicsExplore the lactation function of Protein phosphorylation sites in goat mammary tissues by phosphoproteome
Background: Protein phosphorylation plays an important role in lactation. Differentially modified phosphorylation sites between peak lactation (PL, 90 days postpartum) and late lactation (LL, 280 days postpartum) were investigated using an integrated approach, namely, liquid chromatography with tand...
ORGANISM(S): Capra hircus (Goat) 
2022-02-17 | PXD026437 | Pride
Phosphoproteome  lactation  irs1  β-casein  triglycerides  goat 
UnknownExpression profiling dataset of competing endogenous RNA in pre-eclampsia.
Not available
S-EPMC6881654 | biostudies-literature
ProteomicsMetabolic Reprogramming in Hepatocellular Carcinoma: An Integrated Omics Study of Lipid Pathways and Their Diagnostic Potential
Metabolic Reprogramming in Hepatocellular Carcinoma: An Integrated Omics Study of Lipid Pathways and Their Diagnostic Potential
ORGANISM(S): Homo Sapiens 
2025-03-20 | PXD062049 |
TranscriptomicsTMV-derived Small RNAs Reveals Role for Arabidopsis thaliana RNA-dependent RNA Polymerases in Viral siRNA Biogenesis
Using a crucifer-infecting strain of Tobacco Mosaic Virus (TMV-Cg) and Arabidopsis thaliana as a model system, we analyzed the viral small RNA profile in wild-type plants as well as rdr mutants by applying small RNA deep sequencing technology. Over 100,000 TMV-Cg-specific small RNA reads, mostly of...
ORGANISM(S): Youcai mosaic virus 
2009-03-24 | E-GEOD-12918 | biostudies-arrayexpress
TranscriptomicsCebpa regulates gene transcription in basophils
To investigate the mechanisms by which C/EBPa drives basophil differentiation and maintains basophil identity, we examined whether or not C/EBPa promotes basophil molecular programming and simultaneously represses mast cell molecular programming. We performed genome-wide gene expression profiling on...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-41596 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human T98G cells during cell cycle in T98G
The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D. melanogaster, RB-dependent repression is mediated in part by the multisubunit protein complex Drosophila RBF, E2F, and Myb (dREAM) that contains h...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8537 | biostudies-arrayexpress
UnknownElectrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense.
Not available
S-EPMC4824164 | biostudies-literature
TranscriptomicsIdentification of copper (Cu) stress-responsive grapevine microRNAs and their target genes by high-throughput sequencing
Background: MicroRNAs (miRNAs) are a class of single-stranded non-coding small RNAs (sRNAs) that are 20-24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play important roles in plant growth, development, and stress responses. With more copper (Cu) and copper-containing com...
ORGANISM(S): Vitis labrusca x Vitis vinifera 
2016-02-20 | E-GEOD-78133 | biostudies-arrayexpress
TranscriptomicsCathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection
Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic and degenerative disease in humans. Here, we identified a key cell-intrinsic role for cathepsin B as a negative feedback regulator of lysosomal biogenesis and a...
ORGANISM(S): Mus musculus 
2016-08-04 | E-GEOD-79508 | biostudies-arrayexpress
ProteomicsSC-43 Inhibits Methicillin-resistant Staphylococcus aureus Through Inhibition of Heme Biosynthesis
SC-43 inhibits the key enzyme coproporphyrin ferrochelatase (CpfC) of the coproporphyrin-dependent (CPD) heme synthesis pathway and interferes with the bacterial porphyrin metabolism.
ORGANISM(S): Staphylococcus Aureus 
2026-01-22 | PXD073397 |
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