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MetabolomicsGenome-wide mapping of genetic suppression events in Streptococcus pneumoniae
Historically, suppressor analysis has been a powerful tool for uncovering the functions of essential genes. In this study, we report Sup-seq, a transposon-sequencing technique with random DNA barcodes that enables genome-wide detection of genetic suppression. When applied to seven essential genes in...
2026-09-01 | MTBLS15113 | MetaboLights
UnknownGut fungal landscape in colorectal cancer and its cross-kingdom interplay with gut microbial ecology.
Not available
S-EPMC12907713 | biostudies-literature
ProteomicsSuppression of mosquito Aedes aegypti population using a CRISPR-targeted leucine aminopeptidase 1 mutation
Aedes aegypti are vectors of several devastating arboviruses infecting hundreds of millions of people annually. Controlling mosquito populations by regulating their reproduction is important to minimize viral transmission in the absence of effective antiviral therapies or vaccines. Here, we demonstr...
ORGANISM(S): Aedes Aegypti 
2023-02-05 | PXD039869 |
ProteomicsUrinary proteomics of bladder cancer
LC-MS/MS was used to perform proteomic analysis of preoperative and postoperative urine samples of patients with bladder cancer
ORGANISM(S): Homo Sapiens 
2018-11-29 | PXD011871 |
ProteomicsPSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation
MDA-MB-231 cells with expression of Flag-GPX4 were treated with IFNg. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Homo Sapiens 
2025-03-01 | PXD061373 |
ProteomicsEnergy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
In this project, SILAC-based quantitative proteomics approach was applied for phosphoproteomics analysis. The light samples were treated with ddH2O as control group, and the medium samples labeled by 2D2 of lysine (K4) and 13C6 of arginine (R6) were treated with 2DG, while the heavy samples labeled ...
ORGANISM(S): Homo Sapiens 
2022-11-08 | PXD038034 |
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