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TranscriptomicsAmplicon sequencing of different regions of metastatic melanomas
Genetic heterogeneity can provide tumors with opportunities for therapy evasion, however the degree of genetic heterogeneity within metastatic melanomas has not been thoroughly investigated. We therefore isolated DNA from different regions of formalin fixed paraffin embedded metastatic melanoma tiss...
ORGANISM(S): Homo sapiens 
2013-09-08 | E-MTAB-1794 | biostudies-arrayexpress
TranscriptomicsClonal heterogeneity in melanoma
Genetic heterogeneity is an important feature of solid tumors, however it is often assumed that most cancer cell lines are genetically homogeneous. A disparity in genetic complexity between cell lines and the disease they model could result in problems such as in vitro preclinical experiments overst...
ORGANISM(S): Homo sapiens 
2013-09-08 | E-MTAB-1753 | biostudies-arrayexpress
TranscriptomicsMelanoma Cells Grown in Stem Cell and Serum Media
Cells from patient melanoma samples were grown de novo in either a stem cell media (SCM) or in standard serum containing media, as well as xenografts derived from each culture type. The expression profile of these samples were compared to the expression
ORGANISM(S): Homo sapiens 
2012-07-18 | E-MTAB-741 | biostudies-arrayexpress
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