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TranscriptomicsThe mRNA and microRNA expression profile of the RNA-induced silencing complex in human U-87 astrocytoma cells and primary human astrocytes
mRNA and microRNA expression was examined in global cellular fractions and in RNA-induced silencing complex (RISC)-immunoprecipitated cell fractions in cultured primary human astrocytes (ScienCell) and in cultured human U-87 MG astrocytoma cells (ATCC). ABSTRACT: Background: GW/P bodies are cytoplas...
ORGANISM(S): Homo sapiens 
2011-05-26 | E-GEOD-21514 | biostudies-arrayexpress
TranscriptomicsMouse high grade astrocytoma cells (GL261) treated with neural stem/precursor cell (NPC) conditioned medium or non-conditioned medium (control)
Primary astrocytomas of high histopathological grade (HG-astrocytomas) are largely restricted to older patients and are almost invariably fatal despite multimodal therapy. Here, we show that the young brain has an endogenous defense mechanisms against HG-astrocytomas. Neural precursor cells (NPCs) m...
ORGANISM(S): Mus musculus 
2012-04-30 | E-GEOD-37671 | biostudies-arrayexpress
TranscriptomicsGenotyping by array of anaplastic oligodendroglioma
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net: Anaplastic oligodendrogliomas (AOs) are rare primary brain tumors which are generally incurable with few treatment targets identified. Most oligodendrogliomas have chromosome ...
ORGANISM(S): Homo sapiens 
2015-07-23 | E-MTAB-3457 | biostudies-arrayexpress
TranscriptomicsAn expression profiling study of anaplastic oligodendroglioma
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net): Anaplastic oligodendrogliomas (AOs) are rare primary brain tumors which are generally incurable with few treatment targets identified. Most oligodendrogliomas have chromosome...
ORGANISM(S): Homo sapiens 
2015-07-23 | E-MTAB-2768 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles of anaplastic glioma with or without the mutated IDH1/2 gene
To examine the NRF2 activity in anaplastic glioma with mutated IDH1/2, we conducted the microarray analysis to measure the expression levels of representative NRF2 target genes, including NQO1, HMOX1, GCLM, TXNRD1, and PRDX1. 12 anaplastic gliomas with or without mutated IDH1/2.
ORGANISM(S): Homo sapiens 
2013-12-04 | E-GEOD-52942 | biostudies-arrayexpress
TranscriptomicsRecurrent TCF12 mutations in anaplastic oligodendroglioma (Part II, genotyping by array)
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Anaplastic oligodendrogliomas (AOs) are rare primary brain tumors which are generally incurable with few treatment targets identified. Most oligodendrogliomas have chromosome...
ORGANISM(S): Homo sapiens 
2015-06-15 | E-MTAB-2771 | biostudies-arrayexpress
UnknownA 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma.
Not available
S-EPMC3901657 | biostudies-literature
TranscriptomicsHierarchical synergy of Pten, p53 and Rb pathways in high-grade astrocytoma induced in adult brain
Mutations in the PTEN, TP53 and RB1 pathways are obligate events in the pathogenesis of human glioblastomas, the highest grade of astrocytoma. To investigate synergy between these tumor suppressors in mice, we induced various combinations of compound deletions conditionally in astrocytes and neural ...
ORGANISM(S): Mus musculus 
2011-03-23 | E-GEOD-22927 | biostudies-arrayexpress
Genomics
early-onset anaplastic astrocytoma with Lynch syndrome
PRJNA790740 | ENA
Genomicsundefined
anaplastic astrocytoma with Lynch syndrome: a case report
PRJEB49511 | ENA
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