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TranscriptomicsTranscription profiling time series of Sulfolobus acidocaldarius and Sulfolobus solfataricus after treatment with actinomycin D
Transcription inhibition by actinomycin D. RNA samples extracted at 3, 6, 9, 12, 15 min post actinomycin D. Each cDNA hybridised against reference cDNA from untreated culture.
ORGANISM(S): Sulfolobus solfataricus 
2006-11-08 | E-MEXP-894 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of autumn senescence in populus Leaves
Gene expression profiling in leaves of a free-growing aspen tree (Populus tremula) in Umea in northern Sweden during natural autumn senescence (from August 17 to September 21).
ORGANISM(S): Populus tremula 
2004-03-09 | E-MEXP-93 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae 3' poly(A) site mapping
The use of alternative polyadenylation sites is common and affects the post-transcriptional fate of mRNA, including its stability, localization, and translation. Here we present a method for genome-wide and strand-specific mapping of poly(A) sites and quantification of RNA levels at unprecedented ef...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-10 | E-GEOD-40110 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila early embryos and unfertized eggs to analyze mRNA decay patterns in early development
Comparison of expression profiles in early Drosophila embryos and unfertilised eggs (collection intervals: 30-60 min, 90-120 min and 150-180 min after egg laying). A complete summary file containing normalized data with FLYBASE CG gene identifiers, gene symbols and classifications can be found in E-...
ORGANISM(S): Drosophila melanogaster 
2011-02-11 | E-MEXP-2580 | biostudies-arrayexpress
TranscriptomicsThe yeast osmostress response is carbon source dependent
Adaptation to altered osmotic conditions is a fundamental property of living cells and has been studied in particular detail in the yeast Saccharomyces cerevisiae. Yeast cells accumulate glycerol as compatible solute, controlled at different levels by the High Osmolarity Glycerol (HOG) response path...
ORGANISM(S): Saccharomyces cerevisiae 
2017-02-27 | E-MTAB-5313 | biostudies-arrayexpress
TranscriptomicsStore-operated Ca2+ entry in follicular T cells controls humoral immune responses and autoimmunity
T follicular helper (TFH) cells promote affinity maturation of B cells in germinal centers (GCs), whereas T follicular regulatory (TFR) cells limit GC reaction. Store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels mediated by STIM and ORAI proteins is a fundamental si...
ORGANISM(S): Mus musculus 
2016-03-10 | E-GEOD-79039 | biostudies-arrayexpress
TranscriptomicsGene expression data of pHGG tumor samples
Pediatric high-grade gliomas (pHGGs) harboring the K27M mutation of H3F3A (histone H3.3) are characterized by global reduction of the repressive histone mark H3K27me3 and DNA hypomethylation. Analysis of K27M-induced changes on H3K27me3 occupancy and DNA methylation at differentially expresed genes ...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-49822 | biostudies-arrayexpress
TranscriptomicsThe Prion Protein (PrP) is involved in translation via RNA granule-like mRNPs, a connection which is impaired during neurodegenerative diseases
Cytoplasmic RNA granules have emerged as important elements of posttranscriptional and translational regulation. Stress, germinal and neuronal granules contain RNA-binding proteins capable of self-assembly due to prion-like domains. Hyperassembly mediated by these prion-like domains causes several n...
ORGANISM(S): Mus musculus 
2015-11-01 | E-GEOD-57233 | biostudies-arrayexpress
MetabolomicsGNPS - Dataset Creation from GNPS Molcular Networking - 89895d4507c84596a6a01685bfd8acd4
Molecular Networking of fungal culture extracts from T. erinacei analyzed by LC-MS in positive ion mode
ORGANISM(S): Trichophyton Erinacei (ncbitaxon:523106) 
2021-04-29 | MSV000087335 | GNPS
GenomicsA Genome-Wide Association Study of Peripheral Arterial Disease

The Electronic Medical Record Phenotypes and Community-engaged Genomic Association Study aims to identify genetic variants mediating susceptibility to peripheral arterial disease (PAD). The study leverages a biorepository of blood samples of 1688 PAD cases and 1649 controls, and the electronic ...

phs000203.v1.p1 | EGA
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