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We report here genome-wide analysis of the tumor suppressor p53 binding sites in normal human cells. 743 high-confidence ChIP-seq peaks representing putative genomic binding sites were identified in normal IMR90 fibroblasts using a reference chromatin sample. More than 40 % were located within 2 kb ...
ORGANISM(S): Homo sapiens 
The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53 network that includes p53 levels, binding, expression and chromatin changes under diverse str...
ORGANISM(S): Homo sapiens 
This scRNA-seq data resource contains various clustered and auto-annotated anndata, as well as associated individual and sample metadata, from IBDverse. It consists of over 1.1 million cells from terminal ileal biopsies of 111 patients with Crohn’s disease and 232 healthy controls.
ORGANISM(S): Homo sapiens 
This scRNA-seq data resource contains various clustered and auto-annotated anndata, as well as associated individual and sample metadata, from IBDverse. It consists of over upto 4 million cells from terminal ileal biopsies, rectal biopsies and PMBC samples from 421 individuals, including 125 with Cr...
ORGANISM(S): Homo sapiens 
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