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Metabolomics1H NMR Metabolomics Identifies Underlying Inflammatory Pathology in Osteoarthritis and Rheumatoid Arthritis Synovial Joints
Despite osteoarthritis (OA) and rheumatoid arthritis (RA) being typically age-related, their underlying etiologies are markedly different. We used 1H nuclear magnetic resonance (NMR) spectroscopy to identify differences in metabolite profiles in low volumes of OA and RA synovial fluid (SF). SF was a...
2018-10-11 | MTBLS564 | MetaboLights
UnknownEpidemiology of paediatric pain-related visits to emergency departments in the USA: a cross-sectional study.
Not available
S-EPMC8370556 | biostudies-literature
UnknownEnhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
Not available
S-EPMC8816854 | biostudies-literature
MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
UnknownOncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Not available
S-EPMC5358757 | biostudies-literature
Proteomics- Identification of Gαi2-interacting proteins via affinity pull-down and quantitative mass-spectrometry analysis.
In studying patients with activating GNAI2 mutations, we observed T cell hyperresponsiveness that was independent of cAMP suppression. Therefore, we hypothesized that Gαi2 utilizes alternative signal transduction pathways which might be delineated by identifying its interacting proteins in T cells. ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2024-09-20 | PXD048980 | Pride
Gpcrs G-protein coupled receptors Gnai2 - gαi2 G-protein 
UnknownCell surface vimentin-positive circulating tumor cell-based relapse prediction in a long-term longitudinal study of postremission neuroblastoma patients.
Not available
S-EPMC7839076 | biostudies-literature
UnknownTelotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
Not available
S-EPMC4295770 | biostudies-literature
UnknownDuctal activation of oncogenic KRAS alone induces sarcomatoid phenotype.
Not available
S-EPMC4642517 | biostudies-literature
UnknownBRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers.
Not available
S-EPMC11296921 | biostudies-literature
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