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MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
TranscriptomicsExpression data in whole Arabidopsis seedlings after treatment with Rhizoctonia solani AG8 and AG2-1
Rhizoctonia solani is an economically important soil-borne necrotrophic fungal pathogen, with a broad host range and for which little effective resistance exists in crop plants. Arabidopsis is resistant to the R. solani AG8 isolate but susceptible to R. solani AG2-1. Affymetrix microarray analysis...
ORGANISM(S): Arabidopsis thaliana 
2013-02-01 | E-GEOD-26206 | biostudies-arrayexpress
UnknownAnalysis of Rickettsia typhi-infected and uninfected cat flea (Ctenocephalides felis) midgut cDNA libraries: deciphering molecular pathways involved in host response to R. typhi infection.
Not available
S-EPMC3179627 | biostudies-literature
MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
UnknownAssociation of coronary microvascular dysfunction and cardiac bridge integrator 1, a cardiomyocyte dysfunction biomarker.
Not available
S-EPMC8571552 | biostudies-literature
Transcriptomicsidentification of TGCT genes involved in initiation and maintenance of transformed germ cells.
Initially, we had compared gene expression differences in the embryonic gonads (E13.5) of the 129 and M19 strains by performing microarray analysis. These studies allowed us to identify downregulation of expression of the D19Bwg1357e, Zfp162 and Cox15 genes in the M19 strain. We next decided to exa...
ORGANISM(S): Mus musculus 
2009-12-30 | E-GEOD-14481 | biostudies-arrayexpress
UnknownDIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.
Not available
S-EPMC6521623 | biostudies-literature
UnknownLocal consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study.
Not available
S-EPMC5143183 | biostudies-literature
TranscriptomicsDetection of Cancer with Serum miRNAs on an Oligonucleotide Microarray
Micro RNAs (miRNAs) are a class of small, non-coding RNA species that play critical roles throughout cellular development and regulation. miRNA expression patterns taken from various tissue types often point to the cellular lineage of an individual tissue Arrays for serum miRNA analysis were constru...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-16512 | biostudies-arrayexpress
UnknownHigh Choline Intake during Pregnancy Reduces Characteristics of the Metabolic Syndrome in Male Wistar Rat Offspring Fed a High Fat But Not a Normal Fat Post-Weaning Diet.
Not available
S-EPMC8145686 | biostudies-literature
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