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GenomicsDm-aKG treated Intestinal stem cells NEBNext Enzymatic 5hmC-seq (E5hmC-seq) sequencing and data processing
To analyze aKG-induced Tet mediated changes to DNA hydroxymethylation in intestinal stem cell
ORGANISM(S): Mus musculus 
2025-05-07 | E-MTAB-15115 | biostudies-arrayexpress
TranscriptomicsWhole-genome oxidative bisulfite sequencing and data processing of mouse intestinal stem cells with old and young mitochondria
The intent of the study was to profile the methylome and hydroxymethylome in intestinal stem cells with young mitochondria or old old mitochdondria, to ascertain the potential role of mitochondrial age specific influence on epigenetic regulation of ISCs.
ORGANISM(S): Mus musculus 
2025-05-07 | E-MTAB-15119 | biostudies-arrayexpress
TranscriptomicsBreed DNA-methylation in young offspring chicken with custom NimbleGen tiling array
To analyze DNA-methylation differences between two chicken breeds
ORGANISM(S): Gallus gallus 
2011-05-19 | E-MTAB-649 | biostudies-arrayexpress
TranscriptomicsBreed DNA-methylation in adult parent chicken with custom NimbleGen tiling array
To analyze DNA-methylation differences between two chicken breeds
ORGANISM(S): Gallus gallus 
2011-05-19 | E-MTAB-648 | biostudies-arrayexpress
TranscriptomicsRNA-seq of intestinal epithelial stem cells that have an enrichment of either young or old mitochondria
RNA-seq was performed on FACS-isolated stem cells from the mouse intestinal epithelium. The purpose of the experiment was to compare the transcriptomes of stem cells enriched for recently generated (young) mitochondria and stem cells enriched with old mitochondria. The dataset also includes samples ...
ORGANISM(S): Mus musculus 
2024-05-18 | E-MTAB-13036 | biostudies-arrayexpress
TranscriptomicsBreed gene expression differences in young offspring chicken with Affymetrix Chicken Gene Chip
Heritable epigenetic variation in wild and domesticated chickens. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-644/E-MTAB-644.additional.zip
ORGANISM(S): Gallus gallus 
2011-05-10 | E-MTAB-644 | biostudies-arrayexpress
TranscriptomicsThe fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
Background/Objectives: Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many sm...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-58622 | biostudies-arrayexpress
TranscriptomicsNon-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKβ
Notch signaling is frequently hyperactivated in breast cancer, but how the enhanced signaling contributes to the tumor process is less well understood. In this report, we identify the proinflammatory cytokine interleukin-6 (IL-6) as a novel Notch target in breast tumor cells. Enhanced Notch signalin...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-36051 | biostudies-arrayexpress
GenomicsCohort-Based Genome-Wide Association Study of Glioma (GliomaScan)

We conducted a new independent GWAS of adult glioma using 1,856 cases and 4,955 controls from 14 cohort studies belonging to the Cohort Consortium, 3 case-control studies, and 1 population-based case only study. Cases were newly diagnosed glioma [ICDO-3 codes 9380-9480 or equivalent], and control...

phs000652.v1.p1 | EGA
UnknownAcute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes.
Not available
S-EPMC3220741 | biostudies-literature
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