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GenomicsProfiling of Androgen Receptor in prostate cancer cells in response to androgen deprivation and the onset of the neuroendocrine phenotype
Androgen deprivation therapy (ADT), also called chemical castration, is one of the prevailing treatments of local and metastatic prostate cancer enabling inhibition of the Androgen Receptor (AR) pathway and tumor regression. However, the response to therapy varies among patients with some showing sy...
ORGANISM(S): Homo sapiens 
2025-10-13 | GSE273809 | GEO
ProteomicsComparative proteomic and transcriptomic analysis of the impact of androgen stimulation and darolutamide inhibition on prostate cancer cells
Androgen receptor (AR) signaling is a major driver and therapy target in prostate cancer. Several inhibitors of AR function are approved for different stages of the disease and their impact on downstream gene transcription has been described. However, the ensuing effects of androgen and anti-androge...
ORGANISM(S): Homo sapiens (Human) 
2023-02-17 | PXD036962 | Pride
Andrigen receptor signalling Vcap Darolutamide 
GenomicsProfiling of Androgen Receptor in prostate cancer cells in response to androgen deprivation and the onset of the neuroendocrine phenotype
Profiling of Androgen Receptor in prostate cancer cells in response to androgen deprivation and the onset of the neuroendocrine phenotype
PRJNA1143397 | ENA
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