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ProteomicsAndrographolide sulfonate attenuates acute lung injury by reducing expression of myeloperoxidase and neutrophil-derived proteases in mice
Andrographolide sulfonate (Andro-S), a sulfonation derivative of andrographolide, is known to be effective in treating inflammation-related diseases, while the underlying mechanisms and global protein alterations in response to Andro-S remain unknown. This study aimed to investigate the pharmacologi...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-22 | PXD008552 | Pride
Andrographolide sulfonate Proteomics Acute lung injury Target identification. Itraq 
TranscriptomicsDifferential gene expression of Andrographis paniculata and andrographolide enriched andrographis paniculata extract in liver cells
Andrographis paniculata Nees and its major compound andrographolide is known to exhibit a pleothera of activities. Active component enriched extracts are known to provide various beneficial effects, and therefore it was interesting to investigate whether increased amount of major compound alters gen...
ORGANISM(S): Homo sapiens 
2018-11-06 | GSE74769 | GEO
TranscriptomicsAndrographolide Ameliorates Aortic Lesion via Inhibition of NF-κB Signaling Pathway in Angiotensin-II Treated Murine Model of Abdominal Aortic Aneurysm
Abstract Introduction: Abdominal aortic aneurysm (AAA) is a severe aortic disease with a high mortality rate in the event of rupture. There is an urgent need for pharmacological treatment to address the progression and development of AAA. Andrographolide, a natural anti-inflammatory compound derived...
ORGANISM(S): Mus musculus 
2026-03-30 | GSE292563 | GEO
UnknownLipase catalyzed synthesis of antimicrobial andrographolide derivatives.
Not available
S-EPMC5996720 | biostudies-literature
GenomicsAndrographis paniculata
MeJA regulates andrographolide biosynthesis (PRJCA025783)
PRJDB31301 | ENA
UnknownActivity of andrographolide against chikungunya virus infection.
Not available
S-EPMC4585663 | biostudies-literature
UnknownAndrographolide induces DNA damage in prostate cancer cells.
Not available
S-EPMC6383681 | biostudies-literature
UnknownDevelopment of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study.
Not available
S-EPMC4818061 | biostudies-literature
UnknownAndrographolide, a natural anti-inflammatory agent: An Update.
Not available
S-EPMC9551308 | biostudies-literature
UnknownAndrographolide sensitizes glioma to temozolomide by inhibiting DKK1 expression.
Not available
S-EPMC11473956 | biostudies-literature
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