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TranscriptomicsMycobacteria-Dependent Expression of microRNA-142-3p Reduces WASP Family Proteins and Controls Phagocytosis
Phagocytosis requires the activation of a plethora of mechanisms that include the activation of the actin cytoskeleton guided by the Arp2/3 complex. These are promoted by activators such as the Wiskott Aldrich Syndrome Protein (WASP) family members. In order to further understand the molecular mecha...
ORGANISM(S): Mus musculus 
2013-06-16 | E-GEOD-23429 | biostudies-arrayexpress
TranscriptomicsEffect of Pro- and anti-inflammatory lipids in intracellular survival and killing of mycobacteria
Mouse macrophages J774A.1 were pre-treated with the anti-inflammatory lipid eicosapenaenoic acid (EPA) or the pro-inflammatory lipid ceramide (Cer) for 3h. Macrophages were then infected with Mycobacterium smegmatis for 1h, and total RNA was collected. In a parallel experiment, infected macrophages ...
ORGANISM(S): Mus musculus 
2015-01-20 | E-GEOD-27277 | biostudies-arrayexpress
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