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Transcriptomicssingle cell RNA sequencing of migratory dendritic cells after intranasal adjuvant/tolerogen administration
We compared migratory DCs in draining mediastinal lymph node after intranasal administration of different vaccine adjuvants based on CTA1 subunit of cholera toxin. The goal was to determine different characteristics of dendritic cells subsets after pro-inflammatory vs tolerogenic adjuvant. We had 3 ...
ORGANISM(S): Mus musculus 
2023-05-15 | E-MTAB-12942 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of hemagglutinin specific B cells after influenza virus infection: gene expression data
Understanding dynamics of antigen specific B cell responses and link between BCR and B cell differentiation is crucial for our ability to direct immune responses and to generate memory and plasma cells responses to protective targets. Here we have infected mice with IAV-PR8 and sacrificed them at di...
ORGANISM(S): Mus musculus 
2021-06-22 | E-MTAB-9491 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA, BCR and CITE-Seq of longitudinal COVID-19 patients
6 patients with severe COVID-19 were followed longitudinally during hospitalization and up to 1 year after infection, when they also received a vaccine. For each time point and patient, PBMCs were collected and split into 3 pools: 1/3 was sequenced straight; from 1/3 of the samples B cells were enri...
ORGANISM(S): Homo sapiens 
2022-12-06 | E-MTAB-12392 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of hemagglutinin specific B cells after influenza virus infection: VDJ data
Understanding dynamics of antigen specific B cell responses and link between BCR and B cell differentiation is crucial for our ability to direct immune responses and to generate memory and plasma cells responses to protective targets. Here we have infected mice with IAV-PR8 and sacrificed them at di...
ORGANISM(S): Mus musculus 
2021-06-22 | E-MTAB-9478 | biostudies-arrayexpress
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