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ORGANISM(S): Homo sapiens 
We have employed whole genome microarray expression profiling as a discovery platform to identify genes involved in plaque rupture. Human coronary artery endothelial cells (ECs) were stimulated in vitro for 12 hours with plasma obtained from the coronary sinus (CS) and the aorta (Ao) of patients wit...
ORGANISM(S): Homo sapiens 
20 patients with unstable angina were divided into patient group by using coronary angiography. The sex- and age-matched healthy individuals were enrolled as control group. Venous bloods were collected for extracting RNA. We used the Human Genome U133 plus 2.0 genechip produced by Affymetrix to deta...
ORGANISM(S): Homo sapiens 
Coronary artery disease (CAD) remains a leading cause of death worldwide. Acute coronary syndromes (ACS) are the spectrum of diseases arising from coronary atherosclerotic plaque rupture, ranging from unstable angina (UA; clinical symptoms of cardiac ischemia without myocardial necrosis) to myocardi...
ORGANISM(S): Homo sapiens 
Current methods of stratifying patient risk of myocardial injury and stable angina rely on complex combinations of risk factors that exhibit only limited prognostic power, hence there remains a need to identify biomarkers that can be sampled non-invasively and more accurately predict patient outcome...
ORGANISM(S): Homo sapiens (Human) 
2018-11-06 | PXD006333 | Pride
20 patients with unstable angina were divided into patient group by using coronary angiography. The sex- and age-matched healthy individuals were enrolled as control group. Venous bloods were collected for extracting RNA.
ORGANISM(S): Homo sapiens 
2011-12-31 | GSE34781 | GEO
Genomic variants associated with angina and health status outcome after MI
Genomic variants associated with angina and health status outcome after MI
We profiled miRNA expression in the plasma from healthy subjects and patients with unstable angina pectoris to obtain differentially expressed plasma miRNAs. We randomly selected 25 samples from each group and combined into a sample pool. In this way we obtained 7 and 6 sample pools in control group...
ORGANISM(S): Homo sapiens 
2017-02-08 | GSE94605 | GEO
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