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ProteomicsInteractome of the autoimmune risk gene product ANKRD55
The ankyrin repeat domain-55 (ANKRD55) gene contains intronic single nucleotide polymorphisms (SNPs) associated with risk to contract multiple sclerosis, rheumatoid arthritis or other autoimmune disorders. Risk alleles of these SNPs are associated with higher levels of ANKRD55 in CD4+ T cells. The b...
ORGANISM(S): Homo sapiens (Human) 
2019-09-25 | PXD013332 | Pride
Ankrd55 Ankyrin repeat Multiple sclerosis Rheumatoid arthritis Autoimmune 
GenomicsAutoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [ATAC-Seq]
Autoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [ATAC-Seq]
PRJNA1297113 | ENA
GenomicsAutoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [RNA-Seq]
Autoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [RNA-Seq]
PRJNA1297111 | ENA
TranscriptomicsAutoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [RNA-Seq]
Genome-wide association studies (GWAS) have linked the locus encoding Ankyrin Repeat Domain 55 (ANKRD55) with numerous autoimmune diseases; however, its biological function and role in inflammation are unclear. Here, we demonstrate that Ankrd55-deficient mice are protected from T cell-mediated colit...
ORGANISM(S): Mus musculus 
2025-08-28 | GSE303699 | GEO
GenomicsAutoimmune Disease Risk Gene ANKRD55 Promotes Th17 Effector Function Through Metabolic Modulation [ATAC-Seq]
Genome-wide association studies (GWAS) have linked the locus encoding Ankyrin Repeat Domain 55 (ANKRD55) with numerous autoimmune diseases; however, its biological function and role in inflammation are unclear. Here, we demonstrate that Ankrd55-deficient mice are protected from T cell-mediated colit...
ORGANISM(S): Mus musculus 
2025-08-28 | GSE303700 | GEO
UnknownInteractome of the Autoimmune Risk Protein ANKRD55.
Not available
S-EPMC6759997 | biostudies-literature
UnknownANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
Not available
S-EPMC12520676 | biostudies-literature
UnknownGenomic Multiple Sclerosis Risk Variants Modulate the Expression of the ANKRD55-IL6ST Gene Region in Immature Dendritic Cells.
Not available
S-EPMC8801523 | biostudies-literature
UnknownPositive Association between ANKRD55 Polymorphism 7731626 and Dermatomyositis/Polymyositis with Interstitial Lung Disease in Chinese Han Population.
Not available
S-EPMC5392395 | biostudies-literature
UnknownImpact of Single Nucleotide Polymorphism in the ANKRD55 Gene on Occurrence and Clinical Characteristics of Rheumatoid Arthritis.
Not available
S-EPMC9376995 | biostudies-literature
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