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ProteomicsPancreatic cancer cells treated with anlotinib
Aberrant regulation of angiogenesis involves in the growth and metastasis of tumors, but angiogenesis inhibitors fail to improve overall survival of pancreatic cancer patients in previous phase III clinical trials. A comprehensive knowledge of the mechanism of angiogenesis inhibitors against pancrea...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023344 | Pride
Pancreatic cancer Anlotinib 
ProteomicsPhosphoproteomics Data of pancreatic cancers cells treated with anlotinib
Aberrant regulation of angiogenesis involves in the growth and metastasis of tumors, but angiogenesis inhibitors fail to improve overall survival of pancreatic cancer patients in previous phase III clinical trials. A comprehensive knowledge of the mechanism of angiogenesis inhibitors against pancrea...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023345 | Pride
Phosphoproteomics data Anlotinib Pancreatic cancer 
GenomicsTranscriptome profiling of Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975
Transcriptome profiling of Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975
PRJEB27916 | ENA
TranscriptomicsRole of Anlotinib-induced CCL2 decrease in anti-angiogensis and response prediction for Non-Small Cell Lung Cancer therapy
Purpose: Our previous clinical trials have been demonstrated that Anlotinib can inhibit tumor growth upon refractory advanced non-small cell lung cancer (NSCLC) patients with the possibility mechanism of anti-angiogenesis. The present study sought to reveal the underlying molecular mechanism of Anlo...
ORGANISM(S): Homo sapiens 
2018-11-30 | E-MTAB-5997 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975
Further to our previous study (E-MTAB-5997), here we performed transcriptome profiling on Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975, and would like to understand the effects of Anlotinib on Anlotinib-resistant NCI-H1975 cell, compare the different transcriptom...
ORGANISM(S): Homo sapiens 
2019-07-01 | E-MTAB-7068 | biostudies-arrayexpress
ProteomicsDifferential proteomics analysis on plasma from anlotinib-treated advanced non-small cell lung cancer patients
Anlotinib has been demonstrated to be effective in advanced non-small cell lung cancer (NSCLC) patients. DNA-seq- and RNA-seq-based anlotinib molecular mechanism and biomarker screening have been introduced in previous studies. The underlying value of proteomics for anlotinib study is still unclear....
ORGANISM(S): Homo Sapiens 
2020-03-05 | PXD017919 |
TranscriptomicsGene expression after human SW982 cells treated with anlotinib by a microarray profiling (Affymetrix)
Anlotinib could significantly suppresses synovial sarcoma proliferation in PDTX model and cell lines. To identify potential anlotinib targets in synovial sarcoma, we performed a microarray profiling (Affymetrix) in human SW982 cells treated with anlotinib.
ORGANISM(S): Homo sapiens 
2019-01-01 | GSE109468 | GEO
TranscriptomicsGene expression after human PANC-1 cells treated with anlotinib by a microarray profiling (Affymetrix)
Anlotinib exerted cytotoxity on pancreatic cancer cells. To identify potential anlotinib targets in pancreatic cancer, we performed a microarray profiling (Affymetrix) in human PANC-1 cells treated with anlotinib.
ORGANISM(S): Homo sapiens 
2020-12-21 | GSE163574 | GEO
GenomicsGene expression after human PANC-1 cells treated with anlotinib by a microarray profiling (Affymetrix)
Gene expression after human PANC-1 cells treated with anlotinib by a microarray profiling (Affymetrix)
PRJNA686789 | ENA
TranscriptomicsChromatin accessibility analysis uncovers TFAP2A as a regulator on pro-angiogenesis of acquired resistance to anlotinib
Anlotinib, a multitarget agent a multi-target agent that inhibits tumor proliferation and angiogenesis, has been demonstrated to be effective for non-small cell lung cancer (NSCLC) at third-line or over third-line. However, the underlying mechanisms of anlotinib acquired-resistance is still unclear....
ORGANISM(S): Homo sapiens 
2020-11-09 | GSE142031 | GEO
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