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ProteomicsOxonium ion guided analysis of quantitative proteomics data reveals site-specific O-glycosylation of anterior gradient protein 2 (AGR2)
Developments in mass spectrometry (MS)-based analyses of glycoproteins have been important to study changes in glycosylation related to disease. Recently, the characteristic pattern of oxonium ions in glycopeptide fragmentation spectra had been used to assign different sets of glycopeptides. In part...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025805 | Pride
Glycoproteomics  tmt labeling  oxonium ion  lc−ms/ms  o-glycosylation  colorectal cancer  agr2 
ProteomicsAnterior Gradient protein 2 is a marker of tumor aggressiveness in breast cancer and favors chemotherapy-induced senescence escape.
Among the different chemotherapies available, genotoxic drugs are widely used. In response to these drugs, particularly doxorubicin, tumor cells can enter into senescence. Chemotherapy-induced senescence (CIS) is a complex response. Long described as a definitive arrest of cell proliferation, we and...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028073 | Pride
Chemotherapy Agr2 Senescence 
UnknownAnterior gradient-2 is overexpressed by fibrolamellar carcinomas.
Not available
S-EPMC2746414 | biostudies-literature
TranscriptomicsThe protein disulfide isomerase AGR2 is essential for the production of intestinal mucus
Protein disulfide isomerases (PDIs) aid protein folding and assembly by catalyzing formation and shuffling of cysteine disulfide bonds in the endoplasmic reticulum (ER). Many members of the PDI family are expressed in mammals but the roles of specific PDIs in vivo are poorly understood. A recent hom...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12503 | biostudies-arrayexpress
UnknownCrystal structure of human anterior gradient protein 3.
Not available
S-EPMC6038452 | biostudies-literature
TranscriptomicsThe Anterior Gradient Homolog 3 (AGR3) Gene Is Associated with Differentiation and Survival in Ovarian Cancer
Low-grade serous ovarian carcinoma is believed to arise from serous borderline ovarian tumors, yet the progression from serous borderline tumors to low-grade serous ovarian carcinoma remains poorly understood. The purpose of this study was to identify differentially expressed genes between the two g...
ORGANISM(S): Homo sapiens 
2011-03-04 | E-GEOD-27651 | biostudies-arrayexpress
ProteomicsProtein solubility changes in mouse tibialis anterior during aging
Protein solubility changes in mouse tibialis anterior during aging
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD057317 | Pride
Protein solubility  insolubilome  proteostasis  aging  protein quality control  mouse. 
ProteomicsProtein 2DE reference map of Rhodnius prolixus's anterior midgut, part 2
Rhodnius prolixus is one of the most important vectors of Chagas’ disease caused by the parasite Trypanosoma cruzi. Vector control is the principal combat method of this disease. It is inside of intestine that T. cruzi completes his life cycle to become infectious. On this work a 2D protein map of R...
ORGANISM(S): Rhodnius prolixus (Triatomid bug) 
2015-12-14 | PXD001489 | Pride
Midgut 2d-map Rhodnius prolixus 
UnknownAnterior gradient protein-2 is a regulator of cellular adhesion in prostate cancer.
Not available
S-EPMC3937391 | biostudies-literature
UnknownAnterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells.
Not available
S-EPMC4094684 | biostudies-literature
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