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MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
GenomicsAnthelmintic resistance in Haemonchus contortus and parasite resistance in Dorper, Morada Nova, Santa Ines, and Texel sheep breeds
Parasite-host-environment approach to control anthelmintic resistance in sheep flocks
PRJEB67593 | ENA
TranscriptomicsTranscriptome analysis reveals molecular anthelmintic effects of procyanidins in C. elegans
Worldwide, more than 1 billion people are affected by infestations with soil-transmitted helminths and also in veterinary medicine helminthiases are a severe thread to livestock due to emerging resistances against the common anthelmintics. Proanthocyanidins have been increasingly investigated for th...
ORGANISM(S): Caenorhabditis elegans 
2017-08-31 | GSE101680 | GEO
GenomicsAscarids exposed: gene expression analysis of anthelmintic naïve Parascaris spp. following in vitro drug exposure
Ascarids exposed: gene expression analysis of anthelmintic naïve Parascaris spp. following in vitro drug exposure
PRJNA531629 | ENA
TranscriptomicsAscarids exposed: gene expression analysis of anthelmintic naïve Parascaris spp. following in vitro drug exposure
Ascarid parasites infect a variety of hosts, and control measures rely heavily on anthelmintics raising concerns for anthelmintic resistance. Parascaris spp., the equine ascarid, is the only ascarid with documented substantial drug resistance. Elucidating drug responses of susceptible parasites may ...
ORGANISM(S): Parascaris sp. 
2019-04-10 | GSE129514 | GEO
UnknownEssential Oils as Novel Anthelmintic Drug Candidates.
Not available
S-EPMC9735941 | biostudies-literature
UnknownRepurposing anthelmintic agents to eradicate resistant leukemia.
Not available
S-EPMC7320149 | biostudies-literature
GenomicsUnderstanding gut-microbiome interactions following mass deworming against soil-transmitted helminths (STHs) among young Ethiopian schoolchildren
Microbiome responses to anthelmintic treatment in schoolchildren
PRJEB93790 | ENA
MetabolomicsGNPS Microbial extracts anthelmintic screening
Library of microbial extracts (fungi, bacteria) tested against C. elegans and S. mansoni for anthelmintic activity.
ORGANISM(S): Microbial Extract Library (bacteria, Fungi) 
2023-07-11 | MSV000092398 | GNPS
UnknownRepositioning salicylanilide anthelmintic drugs to treat adenovirus infections.
Not available
S-EPMC6327057 | biostudies-literature
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