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GenomicsMolecular characterization of a precision-cut rat lung slice model for the evaluation of anti-fibrotic drugs
Molecular characterization of a precision-cut rat lung slice model for the evaluation of anti-fibrotic drugs
PRJNA494086 | ENA
UnknownModeling of lung organoid-based fibrosis for testing the sensitivity of anti-fibrotic drugs.
Not available
S-EPMC11899675 | biostudies-literature
ProteomicsIn Vitro Investigation of The Anti-Fibrotic Potential of 1-Phenyl-2-Pentanol, Identified from Moringa Oleifera Lam. on Hepatic Stellate Cells
Liver fibrosis, characterized by excessive extracellular matrix deposition, is driven by activated hepatic stellate cells (HSCs). Due to the limited availability of anti-fibrotic drugs, research con-tinues to explore potential therapeutic agents. Moringa oleifera Lam. (MO), known for its various bio...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD052809 | Pride
Hepatic stellate cell Liver fibrosis Moringa oleifera lam. Molecular docking analysis Proteomics 1-phenyl-2-pentanol Lc-ms/ms 
UnknownEffects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis.
Not available
S-EPMC11011476 | biostudies-literature
UnknownIdentification and characterization of an anti-fibrotic benzopyran compound isolated from mangrove-derived Streptomyces xiamenensis.
Not available
S-EPMC3347021 | biostudies-literature
UnknownTreatment Adherence and Persistence of Anti-Fibrotic Drugs in Real Life in Greece.
Not available
S-EPMC12821729 | biostudies-literature
TranscriptomicsMolecular characterization of a precision-cut rat lung slice model for the evaluation of anti-fibrotic drugs
The translation of novel pulmonary fibrosis therapies from preclinical models into the clinic represents a major challenge demonstrated by the high attrition rate of compounds that showed efficacy in preclinical models but demonstrated no significant beneficial effects in clinical trials. Precision-...
ORGANISM(S): Rattus norvegicus 
2018-10-02 | GSE120679 | GEO
UnknownIntegrated bioinformatics analysis identifies established and novel TGFβ1-regulated genes modulated by anti-fibrotic drugs.
Not available
S-EPMC8866468 | biostudies-literature
UnknownDevelopment and characterization of anti-fibrotic natural compound similars with improved effectivity.
Not available
S-EPMC8891108 | biostudies-literature
UnknownFibrotic microtissue array to predict anti-fibrosis drug efficacy.
Not available
S-EPMC5970268 | biostudies-literature
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