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Plasmid-mediated dissemination of mcr genes has severely compromised colistin efficacy, necessitating adjuvants that restore antibacterial potency without exacerbating toxicity. Despite their essential roles in bacterial survival and virulence, metal ion acquisition systems remain underexplored as t...
2026-08-13 | MTBLS15318 | MetaboLights
Antibiotic adjuvant effects in MRSA USA300
Antibiotic adjuvant effects in VRSA-1
Loratadine's antibiotic adjuvant effects in MRSA 43300
Brominated carbazole's antibiotic adjuvant effects in MRSA 43300
Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health. Rather than depend on creating new antibiotics (to which bacteria will eventually become resistant), we are employing antibiotic adjuvants that potentiation existing antibiotics. To gain biological insight into how...
ORGANISM(S): Staphylococcus aureus 
2025-06-05 | GSE291913 | GEO
Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health. Rather than depend on creating new antibiotics (to which bacteria will eventually become resistant), we are employing antibiotic adjuvants that potentiation existing antibiotics. To gain biological insight into how...
ORGANISM(S): Staphylococcus aureus 
2025-12-10 | GSE308438 | GEO
Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health. Rather than depend on creating new antibiotics (to which bacteria will eventually become resistant), we are employing antibiotic adjuvants that potentiate existing antibiotics. Based on our previous work, loratadin...
ORGANISM(S): Staphylococcus aureus 
2023-03-23 | GSE227099 | GEO
Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health, as the US mortality rate outweighs those from HIV, tuberculosis, and viral hepatitis combined. In the wake of the COVID-19 pandemic, antibiotic resistant bacterial infections acquired during hospital stays have inc...
ORGANISM(S): Staphylococcus aureus 
2022-04-14 | GSE193395 | GEO
Treatment of bacteria with antibiotics at or close to the inhibitory concentration leads to specific transcriptional responses often affecting target genes and targets pathways. A dataset of transcriptional profiles (compendium) induced by antibiotics with known mode-of-action (MoA) can be used to g...
ORGANISM(S): Pasteurella multocida 
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