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ProteomicsRestriction of Arginine Induces Antibiotic Tolerance in Staphylococcus aureus
Staphylococcus aureus is responsible for a substantial number of invasive infections globally each year. These infections are problematic because they are frequently recalcitrant to antibiotic treatment. Antibiotic tolerance, the ability of bacteria to persist despite normally lethal doses of antibi...
ORGANISM(S): Staphylococcus aureus 
2024-07-11 | PXD052440 | Pride
Proteomics Skin and soft tissue infection (ssti) Biofilm Antibiotic treatment failure Tnseq Protein synthesis Staphylococcus aureus 
GenomicsBacterial genomic program to investigate antibiotic treatment failure in Staphylococcus aureus infections
Genomic analysis of treatment failure in Staphylococcus aureus infections
PRJEB85744 | ENA
ProteomicsStress response within the host affects antibiotic persistence and treatment outcome in Staphylococcus aureus infections
Staphylococcus aureus can cause severe invasive infections that require prolonged antibiotic treatment. Although S. aureus can easily acquire antibiotic resistance, even fully susceptible bacteria can persist and survive antibiotic therapy, thus complicating treatment. These so-called persisters are...
ORGANISM(S): Staphylococcus aureus 
2021-09-09 | PXD018372 | Pride
Antibiotic persistence 
TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [Mouse Heart Expression]
Heart failure (HF) is driven via interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. While pathologic gene transactivation in this context is known to be associated with recruitment of histone acetyl-transferases and local chromatin hyperacetylat...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-48110 | biostudies-arrayexpress
UnknownThe association between undetected heteroresistance and antibiotic treatment failure in complicated urinary tract infection.
Not available
S-EPMC11952596 | biostudies-literature
ProteomicsStress adaptation within the host effects antibiotic tolerance and treatment outcome in Staphylococcus aureus infections
Staphylococcus aureus can cause severe invasive infections that require prolonged antibiotic treatment. Although S. aureus can easily acquire antibiotic resistance, even fully susceptible bacteria can persist and survive antibiotic therapy, thus complicating treatment. These so-called persisters are...
ORGANISM(S): Bacteria Staphylococcus aureus 
2021-02-12 | PXD018332 | Pride
Stress response Antibiotic persistence Staphylococcus aureus 
TranscriptomicsTranscriptomic Analysis of Nephrotoxicity Induced by Cephaloridine, a Representative Cephalosporin Antibiotic
Cephaloridine (CER) is a classical beta-lactam antibiotic that has long served as a model drug for the study of cephalosporin antibiotic-induced acute tubular necrosis. In the present study, we analyzed gene expression profiles in the kidney of rats given subtoxic and toxic doses of CER in order to...
ORGANISM(S): Rattus norvegicus 
2010-05-26 | E-GEOD-10034 | biostudies-arrayexpress
UnknownTrends in antibiotic treatment of acute otitis media and treatment failure in children, 2000-2011.
Not available
S-EPMC3852237 | biostudies-literature
UnknownOutpatient Antibiotic Use and Treatment Failure Among Children With Pneumonia.
Not available
S-EPMC11522934 | biostudies-literature
UnknownVariation in Antibiotic Treatment Failure Outcome Definitions in Randomised Trials and Observational Studies of Antibiotic Prescribing Strategies: A Systematic Review and Narrative Synthesis.
Not available
S-EPMC9137992 | biostudies-literature
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