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UnknownAnticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors.
Not available
S-EPMC12424623 | biostudies-literature
ProteomicsEngineered transfer RNAs for suppression of premature termination codons
PTCs cause a multitude of human diseases and there are no established therapeutic options for their therapeutic management. Herein, we report the high-throughput cloning and identification, characterization and functional analysis of anticodon-edited tRNA which display efficacious PTC reversion in ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2019-02-11 | PXD012581 | Pride
Anticodon edited trnas Ptc repair Ace-trnas 
UnknownAnticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons.
Not available
S-EPMC12716684 | biostudies-literature
UnknownOptimization of ACE-tRNAs function in translation for suppression of nonsense mutations.
Not available
S-EPMC11662937 | biostudies-literature
UnknownEfficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs.
Not available
S-EPMC9126842 | biostudies-literature
UnknownEngineered tRNAs efficiently suppress CDKL5 premature termination codons.
Not available
S-EPMC11685654 | biostudies-literature
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