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UnknownRole of lipid trimming and CD1 groove size in cellular antigen presentation.
Not available
S-EPMC1500985 | biostudies-literature
UnknownERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
Not available
S-EPMC6901306 | biostudies-literature
UnknownRationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses.
Not available
S-EPMC3856834 | biostudies-literature
UnknownPreventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Not available
S-EPMC5068242 | biostudies-literature
UnknownEndoplasmic Reticulum Aminopeptidase 1 Is Involved in Anti-viral Immune Response of Hepatitis B Virus by Trimming Hepatitis B Core Antigen to Generate 9-Mers Peptides.
Not available
S-EPMC9115554 | biostudies-literature
UnknownConcerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.
Not available
S-EPMC3815102 | biostudies-literature
ProteomicsAllotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV‐2 S1 Spike Glycoprotein
Cytotoxic T-lymphocytes are critical determinants of SARS-CoV-2 infection severity and long-term immunity. A hallmark of COVID-19 is its highly variable severity and breadth of immune responses between individuals. To address the underlying mechanisms behind this phenomenon we analyzed the proteolyt...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2021-11-25 | PXD027006 | Pride
Peptidomics Allotypic variation Sars-cov‐2 s1 spike glycoprotein Erap1 
UnknownHuman cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1.
Not available
S-EPMC3526977 | biostudies-literature
UnknownFootprints of antigen processing boost MHC class II natural ligand predictions.
Not available
S-EPMC6240193 | biostudies-literature
UnknownNonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum.
Not available
S-EPMC3362685 | biostudies-literature
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