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The objective of this study was to reveal the effects of early life lactoferrin intervention on the liver metabolism in the suckling piglets. Sixty newborn piglets with an average initial body weight (BW) of 1.51 ± 0.05 kg were assigned to the control (CON) group and the lactoferrin (LF) group. P...

2022-03-01 | MTBLS2279 | MetaboLights
The formation of isoAsp residues from Asp and Asn residues in proteins and peptides is accelerated under stressful environments and has detrimental effects on protein structure and function. PROTEIN L-ISOASPARTYL METHYLTRANSFERASE (PIMT) is a protein repairing enzyme which revert such deleterious is...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-12-18 | PXD016240 | Pride
Alcoholic fatty liver disease (AFLD) is a liver disease closely related to long-term alcohol consumption. Although it is known that liver microsomal cytochrome P450 enzyme (CYP450) plays a crucial role in metabolizing alcohol and various exogenous compounds, the specific mechanism by which alcohol a...
ORGANISM(S): Mus Musculus 
Low intensity proton beam irradiation downregulates antioxidative protection in Aspergillus nidulans
The effect of a simulated solar particle event on the fungus Aspergillus nidulans was investigated by exposing surface cultures to a low intensity proton beam (10 pA) and comparing their transcriptomes with those of untreated cultures. Results showed upregulation of DNA repair, ribosome biogenesis, ...
ORGANISM(S): Aspergillus nidulans 
2026-03-04 | GSE294405 | GEO
Targeting DDX3X suppresses progression of KRAS-driven lung cancer by disrupting antioxidative homeostasis and inducing ferroptosis
Targeting DDX3X suppresses progression of KRAS-driven lung cancer by disrupting antioxidative homeostasis and inducing ferroptosis
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