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MetabolomicsA serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome
Antiphospholipid syndrome (APS) is a rheumatic inflammatory chronic autoimmune disease inducing hypercoagulable state associated with vascular thrombosis and pregnancy loss in women. Cardiac, cerebral and vascular strokes in these patients are responsible for reduction in life expectancy. Timely dia...
2017-09-06 | MTBLS356 | MetaboLights
TranscriptomicsTranscriptome profiling of PBMCs from primary antiphospholipid syndrome and systemic lupus erythematosus patients and healthy controls
explore the transcriptome profiles of PBMCs derived from individuals with Primary antiphospholipid syndrome (PAPS) and compared
them with those of healthy individuals. Also compare the transcriptome profiles of the closely related Systemic lupus Erythematosus autoimmune disorder with the same pro...
ORGANISM(S): Homo sapiens 
2008-06-27 | E-MEXP-1635 | biostudies-arrayexpress
TranscriptomicsGene profiling reveals specific molecular pathways in the pathogenesis of atherothrombosis in Antiphospholipid syndrome, Systemic Lupus Erythematosus and Lupus with Antiphospholipid Syndrome
The present gene expression array study of comparative gene profile in monocytes from patients with primary Antiphospholipid Syndrome, Systemic Lupus Erythematosus and Lupus with Antiphospholipid Syndrome demonstrates that the gene expression profiling allows the segregation of these highly related ...
ORGANISM(S): Homo sapiens 
2014-03-12 | E-GEOD-50395 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of Placenta Affected by Antiphospholipid Antibodies: Following the TRAIL of trophoblast death
Antiphospholipid antibodies, a maternal risk factor for preeclampsia, increase shedding of necrotic trophoblast debris from the placenta, leading to endothelial dysfunction. Using Affymetrix HGU133 Plus 2 microarrays, we found changes in the transcriptome of placental explants treated with antiphosp...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-36083 | biostudies-arrayexpress
GenomicsB cells in triple positive antiphospholipid syndrome
B cells in triple positive antiphospholipid syndrome
PRJNA1090881 | ENA
GenomicsGenome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils
Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils
PRJNA512512 | ENA
TranscriptomicsGene profiling reveals specific molecular pathways in the pathogenesis of atherothrombosis in Antiphospholipid syndrome, Systemic Lupus Erythematosus and Lupus with Antiphospholipid Syndrome
The present gene expression array study of comparative gene profile in monocytes from patients with primary Antiphospholipid Syndrome, Systemic Lupus Erythematosus and Lupus with Antiphospholipid Syndrome demonstrates that the gene expression profiling allows the segregation of these highly related ...
ORGANISM(S): Homo sapiens 
2014-03-12 | GSE50395 | GEO
Methylation profilingGenome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thromboembolic events and pregnancy loss. We sought to characterize the DNA methylation profile of primary APS in comparison to healthy controls and individuals with SLE.
ORGANISM(S): Homo sapiens 
2019-01-02 | GSE124565 | GEO
GenomicsInhibiting FKBP5 might alleviate obstetric antiphospholipid syndrome by regulating macrophage polarization.
Inhibiting FKBP5 might alleviate obstetric antiphospholipid syndrome by regulating macrophage polarization.
PRJNA1195595 | ENA
TranscriptomicsWhole Blood Gene Expression Profiles Distinguish Patients with Single versus Recurrent Venous Thromboembolism
Venous thromboembolism (VTE) is a major cause of morbidity and mortality. Pulmonary embolism is a life threatening manifestation of VTE that occurs in at least half the patients on presentation. In addition, VTE recurs in up to 30% of patients after a standard course of anticoagulation, and there i...
ORGANISM(S): Homo sapiens 
2011-11-10 | E-GEOD-19151 | biostudies-arrayexpress
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