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ProteomicsEnhancing the bothropic antivenom through a reverse antivenomics approach
Antivenoms are the only effective treatment for snakebite envenomation and have saved countless lives over more than a century. Despite its value, antivenoms often present risks of adverse reactions. Current formulations contain a substantial fraction of non-specific antibodies and serum proteins th...
ORGANISM(S): Equus Caballus (ncbitaxon:9796) 
2024-11-07 | MSV000096324 | MassIVE
ProteomicsThe preclinical evaluation of a second-generation antivenom for treating snake envenoming in India
In this study, by employing chromatographic purification of the bulk, we have significantly enhanced the preclinical performance of the conventional Indian antivenom product. The effectiveness of the test batches of this ‘second-generation’ antivenom was evaluated using a variety of in vitro and in ...
ORGANISM(S): Equus caballus (Horse) 
2022-04-04 | PXD029436 | Pride
Snakebite Antivenoms Second-generation antivenoms 
UnknownThe paraspecific neutralisation of snake venom induced coagulopathy by antivenoms.
Not available
S-EPMC6123674 | biostudies-literature
UnknownOmics meets biology: application to the design and preclinical assessment of antivenoms.
Not available
S-EPMC4280540 | biostudies-literature
UnknownCross-Neutralisation of In Vitro Neurotoxicity of Asian and Australian Snake Neurotoxins and Venoms by Different Antivenoms.
Not available
S-EPMC5086662 | biostudies-literature
UnknownCost-effectiveness of antivenoms for snakebite envenoming in Nigeria.
Not available
S-EPMC4287484 | biostudies-literature
UnknownCross-reactivity, antivenomics, and neutralization of toxic activities of Lachesis venoms by polyspecific and monospecific antivenoms.
Not available
S-EPMC5560760 | biostudies-literature
UnknownPreclinical efficacy testing of three antivenoms against Naja ashei venom-induced lethality.
Not available
S-EPMC9065424 | biostudies-literature
UnknownTwo snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing.
Not available
S-EPMC9529146 | biostudies-literature
UnknownEfficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies.
Not available
S-EPMC4882578 | biostudies-literature
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