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Strain Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins
Proteomic analysis revealed potential phospho-acceptor sites within Vpx by PIM3. HEK293 cells were transfected with plasmid vector encoding Vpx together with either empty vector or PIM3. Immunoprecipitated Vpx was subjected to liquid chromatography tandem-mass spectrometry.
ORGANISM(S): Homo Sapiens (human) 
Human cytomegalovirus (HCMV) is an important human pathogen and a paradigm of viral immune evasion, targeting intrinsic, innate and adaptive immunity. We have employed two novel, orthogonal multiplexed tandem mass tag-based proteomic screens to identify host proteins downregulated by viral factors e...
ORGANISM(S): Homo sapiens (Human) Cytomegalovirus 
2022-02-22 | PXD026785 | Pride
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