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UnknownThe ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes.
Not available
S-EPMC5491325 | biostudies-literature
UnknownIs mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida?
Not available
S-EPMC8220851 | biostudies-literature
ProteomicsA unique mRNA decapping complex in trypanosomes
Removal of mRNA 5’ caps primes transcripts for degradation and is central for regulating gene expression in eukaryotes. The canonical decapping enzyme DCP2 is stringently controlled by assembly into a dynamic multi-protein complex together with the 5´-3´exoribonuclease Xrn1. Kinetoplastida lack DCP2...
ORGANISM(S): Trypanosoma brucei 
2023-06-14 | PXD038550 | Pride
Xrna Mrna decay Apah-like phosphatase Alph1 Mrna decapping Trypanosoma Exoribonuclease 
ProteomicsImmunoisolation of the trypanosome decapping enzyme ALPH1 delivers a potential subcomplex
Removal of mRNA 5’ caps primes transcripts for degradation and is central for regulating gene expression in eukaryotes. The canonical decapping enzyme DCP2 is stringently controlled by assembly into a dynamic multi-protein complex together with the 5´-3´exoribonuclease Xrn1. Kinetoplastida lack DCP2...
ORGANISM(S): Trypanosoma brucei 
2023-06-14 | PXD042322 | Pride
Xrna Mrna decay Apah-like phosphatase Alph1 Mrna decapping Trypanosoma Exoribonuclease 
UnknownWidespread presence of "bacterial-like" PPP phosphatases in eukaryotes.
Not available
S-EPMC535813 | biostudies-literature
UnknownBacterial-like PPP protein phosphatases: novel sequence alterations in pathogenic eukaryotes and peculiar features of bacterial sequence similarity.
Not available
S-EPMC4091230 | biostudies-literature
UnknownA unique mRNA decapping complex in trypanosomes.
Not available
S-EPMC10415143 | biostudies-literature
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