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ProteomicsBasolateral Protein Scribble Provides Phosphatase PP1 to a Signaling Network Maintaining Apicobasal Polarity
Scribble, a member of the LAP protein family, contributes to the apicobasal polarity (ABP) of epithelial cells. The LAP unique region (LUR) of these proteins is essential for ABP function, and includes a highly conserved Leucine Reach Repeat (LRR) domain. Here we study how the LRR domain of Scribble...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD028919 | Pride
Scribble Apicobasal polarity Phosphatase pp1 
GenomicsDeciphering the molecular alterations sustaining an inverted apicobasal polarity phenotype in colorectal cancer clusters (Tumour Spheres with Inverted Polarity, TSIPs)
Deciphering the molecular alterations sustaining an inverted apicobasal polarity phenotype in colorectal cancer clusters (Tumour Spheres with Inverted Polarity, TSIPs)
PRJNA638924 | ENA
TranscriptomicsDeciphering the molecular alterations sustaining an inverted apicobasal polarity phenotype in colorectal cancer clusters (Tumour Spheres with Inverted Polarity, TSIPs)
Colorectal cancer (CRC) is the second deadliest form of cancer and most of patients die from their metastases. As previously shown by our team, in serrated CRC patients, metastases are due to spherical clusters of epithelial cancer cells displaying an inverted apicobasal polarity. We called them TSI...
ORGANISM(S): Homo sapiens 
2021-01-31 | GSE152299 | GEO
UnknownPar6b regulates the dynamics of apicobasal polarity during development of the stratified Xenopus epidermis.
Not available
S-EPMC3800127 | biostudies-literature
UnknownRab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis.
Not available
S-EPMC9458672 | biostudies-literature
UnknownThe Hippo Pathway Is Essential for Maintenance of Apicobasal Polarity in the Growing Intestine of Caenorhabditis elegans.
Not available
S-EPMC6781910 | biostudies-literature
UnknownVE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation.
Not available
S-EPMC5025268 | biostudies-literature
UnknownKey Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells.
Not available
S-EPMC8273544 | biostudies-literature
UnknownTuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells.
Not available
S-EPMC11136496 | biostudies-literature
UnknownBasolateral protein Scribble binds phosphatase PP1 to establish a signaling network maintaining apicobasal polarity.
Not available
S-EPMC8569552 | biostudies-literature
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