Apobec3g - OmicsDI

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Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes

PRJNA471680 | ENA

Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes

Protein recoding by RNA editing is required for normal health and evolutionary adaptation. However, de novo induction of RNA editing in response to environmental factors is an uncommon phenomenon. While APOBEC3A edits many mRNAs in monocytes/macrophages in response to hypoxia and interferons, the ph...

ORGANISM(S): Homo sapiens

2018-11-22 | GSE114519 | GEO

ARIH2 is a novel Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection

Discovery of novel host-virus interactions leads to a better understanding of mechanisms underlying infection and points to potential therapeutic targets at the interface between virus and host proteins. Recently, global, virus-host interaction networks have been mapped using affinity purification-m...

ORGANISM(S): Homo sapiens (Human)

2019-04-11 | PXD009012 | Pride