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TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
ProteomicsLong-term liver expression of an apolipoprotein A-I mimetic peptide attenuates IFNα-induced inflammation and promotes antiviral activity
Apolipoprotein A-I mimetic peptides are amphipathic alpha-helix peptides that display similar functions to apolipoprotein A-I. Preclinical and clinical studies have demonstrated the safety and efficacy of apolipoprotein A-I mimetic peptides in multiple indications associated with inflammatory proces...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023281 | Pride
Adeno-associated virus Antiviral Apolipoprotein a-i mimetic peptide Liver Type i ifn 
GenomicsApolipoprotein A-I mimetic peptide L37pA attenuates IFNα-induced inflamation and promotes antiviral activity
Apolipoprotein A-I mimetic peptide L37pA attenuates IFNα-induced inflamation and promotes antiviral activity
PRJNA682989 | ENA
TranscriptomicsApolipoprotein A-I mimetic peptide L37pA attenuates IFNα-induced inflamation and promotes antiviral activity
Apolipoprotein A-I mimetic peptides are amphipathic alpha helix peptides that display similar functions to apolipoprotein A-I, and preclinical studies have evaluated . In this study, we evaluated the effect of the long-term expression of L37pA in the liver by an adeno-associated virus (AAV-L37pA) on...
ORGANISM(S): Mus musculus 
2020-12-08 | GSE162764 | GEO
TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alte...
ORGANISM(S): Homo sapiens 
2012-09-30 | GSE36933 | GEO
UnknownApolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p.
Not available
S-EPMC4194270 | biostudies-literature
UnknownThe 5A apolipoprotein A-I (apoA-I) mimetic peptide ameliorates experimental colitis by regulating monocyte infiltration.
Not available
S-EPMC4995292 | biostudies-literature
GenomicsHomo sapiens
Regulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
PRJNA157119 | ENA
UnknownABCA1 (ATP-Binding Cassette Transporter A1) Mediates ApoA-I (Apolipoprotein A-I) and ApoA-I Mimetic Peptide Mobilization of Extracellular Cholesterol Microdomains Deposited by Macrophages.
Not available
S-EPMC5123814 | biostudies-literature
UnknownBioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F.
Not available
S-EPMC4432873 | biostudies-literature
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