Introduction: Aquamin, a multi-mineral product derived from fossilized red marine algae, has been shown to improve colon barrier structure and function. Mesalamine is commonly used as maintenance therapy for patients with mild-to-moderate ulcerative colitis (UC) or those in remission. Our long-term ...
The overall goal of this study was to determine if Aquamin®, a multi-mineral natural product, would alter the expression of proteins involved in growth-regulation and differentiation in the colon. Thirty healthy human subjects (at risk for colorectal cancer) were enrolled in a three-arm, 90-day inte...
Background and aims: Cell-cell adhesion structures (desmosomes and, especially, tight junctions) are known to play important roles in control of transepithelial permeability in the colon. The involvement of cell-matrix interactions in permeability control is less clear. The goals of the present stud...
