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TranscriptomicsTrancription profiling of the hepatoma cell line Huh7 infected with the Hepatitis C Virus
Hepatitis C Virus is a leading cause of chronic liver disease. The identification and characterisation of key host cellular factors that play a role in the HCV replication cycle is important for the understanding of disease pathogenesis and the identification of novel anti-viral therapeutic targets....
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20948 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in human ADPKD cell lines
Changes in gene expression levels were identified by microarray. Samples were human kidney epithelial cell lines derived from patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and unaffected controls. Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common inherited k...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4188 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling in human ADPKD cell lines
Changes in microRNA expression levels were identified by microarray. Samples were human kidney epithelial cell lines derived from patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and unaffected controls. Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common inherit...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4189 | biostudies-arrayexpress
TranscriptomicsThe roles of ppar-delta and ppar-gamma in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
Obesity is a major risk factor for the development of insulin resistance and type II diabetes. The nuclear receptors PPAR delta and PPAR gamma play a central role in regulating metabolism in adipose tissue, as well as being targets for the treatment of insulin resistance. The metabolic effects of PP...
ORGANISM(S): Mus musculus 
2011-07-13 | E-GEOD-26207 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human Hela cells grown under serum starved condtions to identify new targets genes for ETS-domain transcription factor Elk-1
Chromatin immunoprecipitation coupled with microarray analysis (ChIP-chip) was carried out to identify new target genes for ETS-domain transcription factor Elk-1. Experiment was done in Hela cells under serum starved conditions.
ORGANISM(S): Homo sapiens 
2009-08-11 | E-MEXP-1527 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human HeLa cells grown under serum starved conditions to identify new target genes for ETS-domain transcription factor Elk-1
Chromatin immunoprecipitation coupled with microarray analysis (ChIP-chip) was carried out to identify new target genes for ETS-domain transcription factor Elk-1. Experiment was done in Hela cells under serum starved conditions.
ORGANISM(S): Homo sapiens 
2009-08-11 | E-MEXP-2084 | biostudies-arrayexpress
TranscriptomicsRibosome profiling of Tunicamycin-treated and -untreated 17Cl1 cells
Ribosome profiling (RiboSeq) analysis of murine 17 clone 1 (17Cl-1) cells with and without Tunicamycin treatment. Tunicamycin is known to induce the unfolded protein response, and the objective of this work was to assess the impact of Tunicamycin on cellular translation. Additionally, we sought to ...
ORGANISM(S): Mus musculus 
2021-11-09 | E-MTAB-5391 | biostudies-arrayexpress
TranscriptomicsAnalysis of coronavirus and infected host-cell gene expression through RNA sequencing and ribosome profiling
Ribosome profiling (RiboSeq) (maps positions of translating ribosomes on the transcriptome) and RNASeq (quantifies the transcriptome) analysis of murine 17 clone 1 (17Cl-1) cells infected with Murine coronavirus strain A59 (MHV-A59). Samples comprise 1 and 8 h mocks, 1, 2.5, 5 and 8 h post infection...
ORGANISM(S): Mus musculus 
2016-02-08 | E-MTAB-4111 | biostudies-arrayexpress
TranscriptomicsHuman and marmoset trophoblast stem cells differ in signalling requirements and recapitulate divergent modes of trophoblast invasion
We derive experimental conditions for the derivation of marmoset trophoblast like cells. Marmoset naïve PSC form extraembryonic mesoderm in human TSC conditions, whilst TGFβ/NODAL, FGF/ERK and WNT signalling control marmoset peri- and postimplantation trophoblast identity.
ORGANISM(S): Callithrix jacchus 
2024-11-21 | E-MTAB-12463 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of breast cancer cell lines and correlations with fibroblast growth factor receptor (FGFR) signalling and repression
Baseline gene expression profiling of breast cancer cell lines and correlations with FGFR signalling and repression
ORGANISM(S): Homo sapiens 
2011-12-01 | E-MTAB-879 | biostudies-arrayexpress
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